中国药业2017,Vol.26Issue(24):15-18,4.DOI:10.3969/j.issn.1006-4931.2017.24.005
2012年至2015年烟台某医院细菌分布及耐药性分析
Analysis of Distribution and Drug Resistance of Bacteria from 2012 to 2015 in a Hospital in Yantai
刘飞宇 1吴金英 1丁月霞 1孙海燕 1张华芸 1赵泉1
作者信息
- 1. 山东烟台毓璜顶医院,山东烟台 264000
- 折叠
摘要
Abstract
Objective To understand the distribution and drug resistance of bacteria from 2012 to 2015 in a hospital in Yantai,so as to provide a basis for the rational use of antibacterials in clinical.Methods Drug sensitivity tests were tested by VITEK2 Compact or disk diffusion method(K-B method).The data was analyzed by WHONET 5.6 statistical software.Results A total of 26 499 clinical isolates were collected,the top 5 pathogenic bacteria were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa,Acinetobacter baumannii and S taphylococcus aureus.The resistance rates of the first 3 types of bacteria to cefperazone-sulbactam,piperacillin-tazobactam and amikacin were lower.The strains of Acinetobacter baumannii were only lowest to cefoperazone-sulbactam.No Staphylococcus aureus was found to be resistant to vancomycin,linezolid and tegocycline.The antibiotic resistance of major bacteria shows downtrend of year after year (except Acinetobacter baumannii).Conclusion Dynamic monitoring of bacterial resistance changes in the region has important significance for guiding the rational selection of antibacterials and reducing the rate of bacterial resistance.关键词
抗菌药物/细菌/耐药性/合理用药Key words
antibacterials/bacteria/drug resistance/rational drug use分类
医药卫生引用本文复制引用
刘飞宇,吴金英,丁月霞,孙海燕,张华芸,赵泉..2012年至2015年烟台某医院细菌分布及耐药性分析[J].中国药业,2017,26(24):15-18,4.