中国药业2017，Vol.26Issue(24)：42-44,3.DOI:10.3969/j.issn.1006-4931.2017.24.014
辅酶Q10联合多巴丝肼治疗帕金森病60例临床评价
Clinical Evaluation of Coenzyme Q10 Combined with Levodopa and Benserazide Hydrochloride Tablets for Treating Parkinson's Disease in 60 Cases
王丽娟1
作者信息
- 1. 山东省淄博市桓台县人民医院,山东淄博 256400
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy and safety of coenzyme Q 10 combined with Levodopa and Benserazide Hydrochloride Tablets in the treatment of Parkinson's disease and its effect on the quality of life of patients.Methods Totally 120 patients with Parkinson's disease admitted to our hospital from January 2015 to December 2016 were randomly divided into the study group and the control group,60 cases in each group.The control group was given traditional basic drugs such as memantine and donepezil,on this basis,the study group was given coenzyme Q10 combined with Levodopa and Benserazide Hydrochloride Tablets.The two groups were treated for 6 months.Results The total effective rate of the study group was 73.33％,which was significantly higher than 48.33％ of the control group(P ＜ 0.05).After treatment,the MOCA score and BI index score of the study group were higher than those of the control group(P ＜ 0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P ＞ 0.05).Conclusion Coenzyme Q10 in the adjuvant treatment of Parkinson's disease can significantly improve the cognitive impairment and emotional disorders in patients,it has good curative effect and less adverse reactions,and can greatly improve the quality of life of patients,which is worthy of clinical promotion.关键词
辅酶Q10/多巴丝肼/帕金森病/生活质量/临床疗效/安全性Key words
coenzyme Q 10/Levodopa and Benserazide Hydrochloride Tablets/Parkinson's disease/quality of life/clinical effect/safety分类
医药卫生引用本文复制引用
王丽娟..辅酶Q10联合多巴丝肼治疗帕金森病60例临床评价[J].中国药业,2017,26(24):42-44,3.
