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右美托咪定用于臂丛神经阻滞麻醉上肢手术的效果及对患者认知功能的影响

袁志军 傅文敏 周盼

中国医院用药评价与分析2017,Vol.17Issue(11):1520-1521,1524,3.
中国医院用药评价与分析2017,Vol.17Issue(11):1520-1521,1524,3.DOI:10.14009/j.issn.1672-2124.2017.11.027

右美托咪定用于臂丛神经阻滞麻醉上肢手术的效果及对患者认知功能的影响

Anesthesia Effect of Dexmedetomidine in Brachial Plexus Block Anesthesia of Upper Limb Surgery and Its Influence on Cognitive Function

袁志军 1傅文敏 1周盼1

作者信息

  • 1. 江西省分宜县中医院麻醉科,江西分宜 336600
  • 折叠

摘要

Abstract

OBJECTIVE:To probe into the anesthesia effect of dexmedetomidine in brachial plexus block anesthesia of upper limb surgery and its influence on cognitive function .METHODS:80 patients undergoing brachial plexus block anesthesia of upper limb surgery admitted into the Jiangxi Fenyi County Traditional Chinese Medicine Hospital form Jul . 2015 to Jul .2017 were selected and divided into observation group and control group via random number table , with 40 cases in each .The control group was given ropivacaine combined with lidocaine for anesthesia , while the observation group was given dexmedetomidine based on the control group .Differences in heart rates and mean arterial pressures between two groups before and after anesthesia were compared , the onset time and maintenance time of motor nerve blocking and sensory nerve blocking , changes of scores of cognitive function of two groups were observed .RESULTS:40 min after anesthesia , the heart rates and mean arterial pressures of both groups were significantly lower than those of 10 min before anesthesia , but those of the observation group were significantly higher than the control group , with statistically significant difference (P<0.05);there was no statistical significance in the difference of onset time of motor nerve blocking and sensory nerve blocking between two groups ( P >0.05 ); the maintenance time of motor nerve blocking and sensory nerve blocking of the observation group was significantly longer than those of control group , with statistically significant difference (P<0.05);there was no statistical significance in the difference of score of cognitive function between two groups before and 48 h after anesthesia (P>0.05).At 0.5 h and 24 h after anesthesia, score of cognitive function of observation group was significantly higher than that of the control group , with statistically significant difference (P<0.05).CONCLUSIONS:The anesthesia effect of dexmedetomidine in brachial plexus block anesthesia of upper limb surgery is remarkable , which can significantly promote the recovery of patients ' cognitive function .

关键词

上肢手术/臂丛神经阻滞麻醉/右美托咪定/认知功能

Key words

Upper limb surgery/Brachial plexus block anesthesia/Dexmedetomidine/Cognitive function

分类

医药卫生

引用本文复制引用

袁志军,傅文敏,周盼..右美托咪定用于臂丛神经阻滞麻醉上肢手术的效果及对患者认知功能的影响[J].中国医院用药评价与分析,2017,17(11):1520-1521,1524,3.

中国医院用药评价与分析

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1672-2124

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