重庆医学2017，Vol.46Issue(30)：4196-4199,4203,5.DOI:10.3969/j.issn.1671-8348.2017.30.007
磁共振弥漫张量成像对儿童弥漫性轴索损伤程度评估的定量研究
A quantitative study on evaluation of child diffuse axonal injury severity by using MR diffusion tensor imaging
摘要
Abstract
Objective To compare the value of fractional anisotropy(FA)of MR diffusion tensor imaging(DTI) and Glasgow coma scale(GCS) at admission for judging the injury severity and prognosis of diffuse axonal injury (DAI). Methods Thirty-four patients with DAI adopted the GCS score to evaluate the conscious disturbance levels at admission and conducted the DTI examination within 2 weeks. Twenty-three individuals undergoing healthy physical examination conducted the DTI examination. The FA values of visuality lesion area in various sites,healthy side symmetric site and cerebral midline site were measured. The reduction degree of mean FA value at midline site and visuality lesions were measured. The correlation between GCS score,mean FA value reduction degree in visuality lesions and mean FA value at cerebral midline site with consciousness disorder time and recovery degree in half a year after injury was analyzed. Results The reduction degree of mean FA value at cerebral midline site was significantly correlated with consciousness disorder time and recovery degree in half a year after injury(r= 0. 519,P=0. 002; r= 0. 669, P=0. 000) ;the mean FA value reduction degree in visuality lesions and GCS score had low or weak correlation with consciousness dis order time and recovery degree in half a year after injury(r=0. 285,P=0. 103;r=0. 487,P=0. 003;r= -0. 241,P=0. 169;r=-0. 229,P=0. 192). The correlation between mean FA reduction degree in cerebral midline site and mean FA value reduction degree in visuality lesions with the recovery degree in a half years after injury was higher than that in GCS score. Conclusion DTI is a sensitive sequence for diagnosing DAI and has much more value for judging the injury degree and prognosis than the GCS score generally adopted by clinic.关键词
弥漫性轴索损伤/磁共振成像,弥漫/各向异性分数/格拉斯哥意识障碍量表Key words
diffuse axonal injury/magnetic resonance imaging/diffusion/fractional anisotropy/Glasgow coma scale引用本文复制引用
张雨婷,李禄生,何玲,蔡金华,梁平,李映良,翟瑄..磁共振弥漫张量成像对儿童弥漫性轴索损伤程度评估的定量研究[J].重庆医学,2017,46(30):4196-4199,4203,5.基金项目
重庆市科委科技攻关(应用技术研发类)基金资助项目(cstc2012gg-yyjs10013). （应用技术研发类）
