口腔疾病防治2017，Vol.25Issue(12)：784-787,4.DOI:10.12016/j.issn.2096-1456.2017.12.007
种植体周围炎龈沟液中sTREM-1水平的检测
Detection of sTREM-1 levels in gingival crevicular fluid of peri-implantitis
摘要
Abstract
Objective To investigate the relationship between the level of the soluble triggering receptor expressed on myeloid cell (sTREM-1) in the gingival crevicular fluid (GCF) of individuals and peri-implantitis.Methods 46 patients (75 implants) with different severities of peri-implantitis and 18 patients (75 implants) without peri-implantitis were selected in this study.The concentrations of sTREM-1 in GCF with different types of peri-implantitis were detected by enzyme-linked immunosorbent assay (ELISA).The peri-implantitis peroxidase depth (PPD),the distance from the shoulder of the implant to the bottom of the bony defect (DSB),the modified sulcus bleeding index (mSBI) and the modified plaque index (mPLI) were recorded.The correlation between PPD,DSB,mSBI,mPLI and sTREM-1 was analyzed.Results The concentrations of sTREM-1 in GCF in mild,moderate and severe peri-implantitis group were significantly higher than those in healthy group (P ＜ 0.05).The concentrations of sTREM-1 in GCF in severe peri-implantitis group were significantly higher than those in mild and moderate group (P ＜ 0.05).There was no significant difference in the concentration of sTREM-1 in GCF between mild peri-implantitis group and moderate group (P ＞ 0.05).In addition,there was a significant positive correlation between the concentration of sTREM-1 and PPD,DSB,mSBI,mPLI.Conclusions The concentration of sTREM-1 in GCF is closely related to the severity of tissue inflammation around implant.关键词
种植体周围炎/龈沟液/sTREM-1/mSBI/PPDKey words
Peri-implantitis/Gingival crevicular fluid/sTREM-1/mSBI/PPD分类
医药卫生引用本文复制引用
郑德春,吴东..种植体周围炎龈沟液中sTREM-1水平的检测[J].口腔疾病防治,2017,25(12):784-787,4.基金项目
福建省医学创新课题基金资助项目(2015-CX-30) （2015-CX-30）
莆田学院科研基金项目(2016050) （2016050）
