海南医学院学报2017，Vol.23Issue(24)：3449-3451,3455,4.DOI:10.13210/j.cnki.jhmu.20171220.009
急性脑梗死患者侧支循环的脑血管造影评估及其与神经功能损伤程度的相关性
The cerebral angiography of collateral circulation in patients with acute cerebral infarction and its correlation with nerve injury
摘要
Abstract
Objective:To assess the cerebral angiography of collateral circulation in patients with acute cerebral infarc-tion and investigate its correlation with nerve injury.Methods:78 patients with acute cerebral infarction who were treated in the hospital between January 2015 and June 2017 were divided into collateral circulation group(n=47)and no collateral circulation group(n=31)after cerebral angiography.The differences in serum levels of nerve injury markers,neurotrophy indexes and oxidative stress indexes were compared between the two groups.Results:Serum nerve injury markers Copeptin,H-FABP, S100B and MBP levels of no collateral circulation group were significantly higher than those of collateral circulation group;ser-um neurotrophy indexes BDNF and NGF levels were significantly lower than those of collateral circulation group;serum oxida-tive stress indexes 8-OHdG and LHP levels were higher than those of collateral circulation group whereas SOD and CAT levels were lower than those of collateral circulation group.Conclusion:Cerebral angiography can accurately assess the existence of collateral circulation in patients with acute cerebral infarction,and the cerebral injury is more serious in those without collateral circulation.关键词
急性脑梗死/脑血管造影/神经损伤标志物/神经营养/氧化应激Key words
Acute cerebral infarction/cerebral angiography/nerve injury markers/neurotrophy/oxidative stress分类
医药卫生引用本文复制引用
但霞..急性脑梗死患者侧支循环的脑血管造影评估及其与神经功能损伤程度的相关性[J].海南医学院学报,2017,23(24):3449-3451,3455,4.基金项目
凉山州科知局科技计划项目(16YYJS0008)The Liangshan State Bureau of science and technology project(16YYJS0008) （16YYJS0008）
