军事医学2017，Vol.41Issue(9)：745-748,751,5.DOI:10.7644/j.issn.1674-9960.2017.09.011
长航对舰载保存去白细胞悬浮红细胞生化指标的影响
Biochemical indices of red blood cells in additive solution leukocytes reduced preserved in navy ship force during a long voyage
史大川 1郑长青 1姚雪 1石磊 1李燕 1刘伟 1孙伟杰 1韩颖 2刘敏霞 2王东根2
作者信息
- 1. 解放军401医院输血科,山东青岛 266071
- 2. 军事医学科学院野战输血研究所,全军血液安全与保障重点实验室,血液安全保障技术研究北京市重点实验室,北京 100850
- 折叠
摘要
Abstract
Objective To explore the influence on and changes in the biochemical indices of red blood cells(RBCs)in additive solution leukocytes reduced preserved in navy ship force on a long voyage.Methods According to the Requirement of Health Examination for Blood Donors(GB 18467 -2011),RBCs in additive solution leukocytes reduced were prepared from 10 healthy voluntary blood donators one day before sailing.Each blood sample was divided into two parts,one in test group and another in control group.All the groups had samples taken for the biochemical index detection after 1,3,5,7,14 and 21 days of sailing respectively.Results ①The change in total protein(P=0.235)and albumin (P=0.119)concentration was not obvious,and the difference between the two groups was not significant.②The change in total creatinine(P=0.001)and uric acid(P=0.001)concentration was obvious, but the difference between the two groups was not significant.③The change in total cholesterol(P=0.354)concentration was not obvious,but the change in triglycerides(P=0.005)concentration was significant.The difference between the two groups was not significant.④The concentration of lactate dehydrogenase, hydroxybutyrate dehydrogenase and creatine kinase increased with the time of preservation(P<0.001).The difference between the two groups was not significant.⑤The interaction between grouping effect and time effect had no significant influence on the concentration of osmolarity(OSM)(P=0.968)and glucose(Glu) (P=0.406).Between the two groups,the difference of concentrations of OSM(P=0.569)and Glu(P=0.115)was not significant.Conclusion Under the 4 class sea conditions, a long voyage has some impact on the storage of RBCs in additive solution leukocytes reduced,as in the conventional blood storage refrigerator(4 ±2)℃.The results of this study have important clinical implications for our further study of marine blood support.关键词
长航/去白细胞悬浮红细胞/生化指标/舰载保存/血液保存/红细胞/运输Key words
long voyage/red blood cells in additive solution leukocytes reduced/biochemical index/conservation in navy ship force/blood preservation/erythrocytes/transportation分类
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史大川,郑长青,姚雪,石磊,李燕,刘伟,孙伟杰,韩颖,刘敏霞,王东根..长航对舰载保存去白细胞悬浮红细胞生化指标的影响[J].军事医学,2017,41(9):745-748,751,5.
