南京医科大学学报（自然科学版）2017，Vol.37Issue(11)：1433-1436,4.DOI:10.7655/NYDXBNS20171113
B型利钠肽含量对感染性休克患者早期液体复苏容量负荷的评估价值
The predictive value of B type natriuretic peptide in evaluating fluid volume in the patients receiving fluid resuscitation with early phase of septic shock
彭清云 1王林华 1赵宏胜 1陆洋1
作者信息
- 1. 南通大学附属医院重症医学科,江苏南通226001
- 折叠
摘要
Abstract
Objective:To investigate the predictive value of B type natriuretic peptide in evaluating fluid volume in the patients receiving fluid resuscitation with early phase of septic shock,and to find the relative markers of fluid volume which can accurately reflect the blood volume of septic shock.Methods:A prospective study was performed on 60 patients with septic shock enrolled in the intensive care unit of our hospital.All the patients receiving early goal-directed therapy(EGDT),the hemodynamic parameters such as intrathoracic blood volume index (ITBVI),global end diastolic volume index (GEDVI),extravascular lung mater index (EVLWI) were record by using PICCO system before and after EGDT,and the parameters of BNP were record at the same time.The correlations between changes in BNP and changes in ITBVI,GEDVI and EVLWI were tested by Pearson correlation analysis.Results:ITBVI,GEDVI and BNP in all patients were significantly elevated after EGDT.BNP level was not correlated with ITBVI,GEDVI and EVLWI at the time point 0 h and 6 h in the 60 patients receiving fluid resuscitation.The changes in BNP (△BNP) showed significant correlation with changes in △ITBVI and △GEDVI.△EVLWI was not correlated with △BNP.Conclusion:The predictive value of B type natriuretic peptide in evaluating fluid volume in the patients receiving fluid resuscitation with early phase of septic shock is uncertain.关键词
BNP/感染性休克/容量负荷Key words
B type natriuretic peptide/septic shock/fluid volume分类
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彭清云,王林华,赵宏胜,陆洋..B型利钠肽含量对感染性休克患者早期液体复苏容量负荷的评估价值[J].南京医科大学学报（自然科学版）,2017,37(11):1433-1436,4.
