热带作物学报2017，Vol.38Issue(9)：1764-1767,4.DOI:10.3969/j.issn.1000-2561.2017.09.030
4种石斛的多糖对高血压大鼠降血压的影响
Antihypertensive Effects of Polysaccharides from Four Dendrobium Species on Hypertensive Rats
摘要
Abstract
To investigate the antihypertensive activities of the polysaccharides from the stems of 4 Dendrobium species (Dendrobium officinale,Dendrobium nobile,Dendrobium wardianum and Dendrobium Second Love ‘Tokimeki’),the antihypertensive effects of crude polysaccharides,purified polysaccharides and polysaccharide fractions were determined by hypertensive rats in this study.The results showed that all polysaccharides from the 4 Dendrobiumn species had antihypertensive effects on spontaneously hypertensive rats (SHR),and they significantly decreased blood pressure in rats with the increasing of polysaccharide purity or time extention,and significantly higher than nifedipine (positive control) after treatment for 240 min.The antihypertensive effects of the polysaccharide fractions from D.nobile were better than the crude polysaccharides and purified polysaccharides,while the three kinds of polysaccharides were insignificant in D.officinale,D.wardianum or D.Second Love ‘Tokimeki’.Among the 4 polysaccharide fractions from the 4 species,there was no significant difference to reduce blood press.It was suggested that all polysaccharides from the 4 Dendrobium species showed certain antihypertensive activities,and the polysaccharide fractions had better antihypertensive effects,which had a good medicinal prospect.关键词
石斛/多糖/高血压大鼠/降血压活性Key words
Dendrobium/polysaccharides/hypertensive rats/antihypertensive activity分类
医药卫生引用本文复制引用
王再花,叶庆生,李杰,章金辉,徐晔春..4种石斛的多糖对高血压大鼠降血压的影响[J].热带作物学报,2017,38(9):1764-1767,4.基金项目
广东省农业标准化研究项目“铁皮石斛有机种植标准研制” （）
国家青年科学基金(No.31400597) （No.31400597）
广东省科技计划项目(No.2013B020302009) （No.2013B020302009）
广东省园林花卉种质创新综合利用重点实验室开放课题项目(No.HY201501). （No.HY201501）
