四川医学2017，Vol.38Issue(11)：1314-1317,4.DOI:10.16252/j.cnki.issn1004-0501-2017.11.024
老年心力衰竭合并肺部感染患者BNP、NT-proBNP、PCT、NT-proBNP/BNP比值水平变化及意义
Changes and Significance of BNP,NT-proBNP,PCT,NT-proBNP/BNP Ratio in Elderly Patients with Heart Fail-ure Complicated with Pulmonary Infection
余微 1程幼夫 1张汝2
作者信息
- 1. 四川省肿瘤医院健康管理中心,四川成都,610041
- 2. 成都军区总医院老年科,四川成都,610083
- 折叠
摘要
Abstract
Objective To investigate the changes and significance of B type natriuretic peptide(BNP),amino terminal B type natriuretic peptide(NT-proBNP), procalcitonin(PCT), the ratio of NT-proBNP/BNPin elderly patients with heart failure complicated with pulmonary infection, to provide a reference for the clinical evaluation of the severity of heart failure patients. Methods 276 cases of patients with heart failure admitted to the hospital from December 2012 to December 2015 were divided in-to infection group(130 cases)and non infection group(146 cases), according to the occurrence of pulmonary infection.The differences of the ratio of PCT,NT-proBNP,BNP,NT-proBNP/BNP and the relationship between the indexes and cardiac function were analyzed in the two groups.Results The PCT,NT-proBNP/BNP ratio and NT-proBNP in the infection group were signifi-cantly higher than those in the non infection group(P<0.05),but there was no significant difference between the two groups in the level of BNP(P>0.05);The levels of PCT,BNP and NT-proBNP in patients with pulmonary infection increased with the in-crease of cardiac function(P<0.05),and there was no significant difference in NT-proBNP/BNP ratio between patients with dif-ferent functional grades(P>0.05);The ratio of NT-proBNP/to BNP in the infection group was positively correlated with PCT (r=0.621,P<0.05),and there was no significant correlation between BNP,NT-proBNP and PCT(P>0.05).Conclusion Ratio of NT-proBNP/BNP can reflect the severity of infection in elderly heart failurepatients complicated with pulmonary infection because it is not affected by cardiac function.关键词
心力衰竭/心功能/肺部感染/PCT/BNPKey words
heart failure/cardiac function/pulmonary infection/PCT/BNP分类
医药卫生引用本文复制引用
余微,程幼夫,张汝..老年心力衰竭合并肺部感染患者BNP、NT-proBNP、PCT、NT-proBNP/BNP比值水平变化及意义[J].四川医学,2017,38(11):1314-1317,4.
