物理化学学报2017，Vol.33Issue(12)：2377-2387,11.DOI:10.3866/PKU.WHXB201706096
量子点与蛋白质相互作用热力学
Thermodynamics of the lnteractions between Quantum Dots and Proteins
摘要
Abstract
Quantum dots (QDs) exhibit excelent properties, such as broad absorption, narrow emission , high photoluminescence quantum yields, tunable emission wavelength, and anti-photobleaching. As a result, QDs have important applications in biological imaging, tracking, and sensing. When QDs enter living systems, they first encounter proteins. The interactions between proteins and QDs significantly influence the structures and functions of the proteins, as wel as the performance of the QDs in applications. Studies on the interactions between QDs and proteins can provide a theoretical basis for the design, efficient application, and safety evaluation of QDs. Herein we have summarized methods for characterizing thethermodynamics of QD-protein interactions, on the basis of previous work by both our group and others. We also highlight the thermodynamic mechanisms of the QD-protein interactions.关键词
量子点/蛋白质/相互作用/热力学/荧光猝灭Key words
QDs/Protein/Interaction/Thermodynamics/Fluorescence quenching分类
化学化工引用本文复制引用
颜稔,赖璐,许子强,蒋风雷,刘义..量子点与蛋白质相互作用热力学[J].物理化学学报,2017,33(12):2377-2387,11.基金项目
The project was supported by the National Science Foundation of China (21573168, 21303126, 21473125, 21403017, 21603067) and National Science Fund for Distinguished Young Scholars, China (21225313).国家自然科学基金(21573168, 21303126, 21473125, 21403017, 21603067)和国家杰出青年科学基金(21225313)资助项目 （21573168, 21303126, 21473125, 21403017, 21603067）
