摘要
Abstract
Objective:To investigate the relationship between area under the curve (AUC) of glucose tolerance teat (OGTT) and pregnancy outcomes in pregnant women with gestational diabetes mellitus ( GDM ) . Methods:937 cases of pregnant women with GDM who underwent prenatal examination in the First People ' s Hospital of Kunshan from Jan. 2016 to Dec. were analyzed respectively. According to AUC, women were divided into AUC<16. 80mmol/(L·h)group(group A) and AUC≥16. 80mmol/(L·h)group(group B). The differ-ences between the two groups of pregnancy complications,insulin use were analyzed,including the correlation analysis of AUC and neonatal birth weight in AUC≥16. 80mmol/(L·h)group. Result:Of 937 GDM pregnant women,603 were in group A (64. 35％) and 334 were in group B (35. 65％). In the comparison of pregnancy complications,the incidence of premature rup-ture of membrane,pregnancy induced hypertension,macrosomia,neonatal asphyxia rate,the use of insulin were significantly higher in Group B than those in Group A(P<0. 05). While in pre-mature birth,the hypothyroidism,there was no significant difference (P>0. 05). AUC in Group B was significantly associated with neonatal birth weight in GDM pregnant women (r=0. 120,P=0. 033). Conclusions:As the evaluation index of the blood glucose level,when the OGTT time-blood glucose curve area is more than 16. 80mmol/(L·h),the incidence of adverse preg-nancy outcome will increase,and it is significantly related to neonatal birth weight. According to the OGTT time-blood glucose curve area,the pregnant women can be divided into different lay-ers.关键词
妊娠期糖尿病/口服葡萄糖耐量试验/时间-血糖曲线下面积/妊娠结局/新生儿出生体重Key words
Gestational diabetes mellitus/OGTT/Time-blood glucose curve/Pregnant outcomes/Neonatal birth weight分类
医药卫生
