畜牧兽医学报2017，Vol.48Issue(12)：2225-2231,7.DOI:10.11843/j.issn.0366-6964.2017.12.001
环境因素引起的哺乳动物跨代DNA甲基化修饰现象
The Study of Influence of Environment on Transgenerational Inheritance of DNA Methylation in Mammals
摘要
Abstract
Classical genetics suggests that the genetic information of the organism is determined by the genes,that is,only the change of DNA sequence can be inherited,but the epigenetic DNA modifications can't be inherited because of the cell reprograming.Recent studies have found that some of the epigenetic modification caused by environmental factors can also be passed to the offspring,and DNA methylation is one of the main mechanisms of epigenetic modification,which is a hot spot in the transgenerational inheritance field.Herein,we focus on the transgenerational inheritance of DNA methylation caused by environmental factors,which may provide some references for further study on transgenerational inheritance.关键词
DNA甲基化/表观遗传修饰/跨代遗传/环境因素/哺乳动物Key words
DNA methylation/epigenetic modification/transgenerational inheritance/environmental factors/mammals分类
生物科学引用本文复制引用
甘麦邻,杨大洪,谭娅,杨琼,蒲红州,张顺华,朱砺..环境因素引起的哺乳动物跨代DNA甲基化修饰现象[J].畜牧兽医学报,2017,48(12):2225-2231,7.基金项目
四川省科技支撑计划项目(16ZC2838 （）
2016NZ0089) （）
四川省科技富民强县专项行动计划项目(2015NZ0013) （2015NZ0013）
四川省教育厅科研项目(16ZB0038) （16ZB0038）
