肝胆胰外科杂志2018，Vol.30Issue(1)：26-30,5.DOI:10.11952/j.issn.1007-1954.2018.01.007
无功能性胰腺神经内分泌肿瘤的MRI表现及治疗
MRI characteristics and treatment of non-functioning pancreatic neuroendocrine neoplasms
沈威 1马周鹏 2林观生 2陈炳叶 3周建军4
作者信息
- 1. 温州医科大学附属慈溪医院 放射科,浙江 宁波 315300
- 2. 上海市金山区中西医结合医院放射科,上海201501
- 3. 上海市金山区中西医结合医院普外科,上海201501
- 4. 复旦大学附属中山医院 放射科,上海 200032
- 折叠
摘要
Abstract
Objective To explore the MRI characteristics and therapy of non-functioning pancreatic neuroend-ocrine neoplasms (NF-pNENs) and to improve the diagnostic and therapeutic level. Methods The MRI and clinical data of 11 cases of NF-pNENs proved by pathology were analyzed retrospectively. Results All 11 cases were single tumor. Seven cases were viewed as oval while 4 cases were irregular and with lobes. Seven cases showed clear boundary while 4 cases showed local infiltration of adjacent tissue with undefined edge. The maximum diameter of the tumors was 23～137 mm and the mean value was 60.1 mm. There were 5 solid tumors, 5 solid-cystic tumors and 1 cystic tumor among the 11 cases. The unenhanced MRI of the solid area showed asymmetrical mild low signal on T1WI and mild high signal on T2WI, while the cystic area showed T1WI low and T2WI high signal. All tumors showed asymmetrical high signal on DWI. In the solid area, 7 cases showed obvious enhancement continuously, 3 cases showed moderate continuous enhancement and 1 case showed mild delayed enhancement on dynamic enhanced MRI. Complete or uncomplete membrane structure with obvious enhancement can be seen in the tumors of 9 cases. Three cases showed dilation of main duct of pancreas and/or central bile duct. Three cases were accompanied with liver metastasis and 2 cases were accompanied with retroperitoneal lymph node metastasis, and a small amount of ascites were presented in 2 cases. All the 11 cases underwent surgical treatment, and 9 of them obtained radical resection. Seven cases accepted systemic chemotherapy, while the rest 4 cases only received treatment of traditional Chinese medicine. All the 11 cases were followed from 6 to 63 months after surgery. Three cases died with mean survival time of 35.7 months and the rest 8 cases survived. Conclusion MRI can detect the pathological changes of NF-pNENs and it has important value for the diagnosis. Surgery is the main solution for NF-pNENs and radical resection should be performed as early as possibly once the diagnosis is confirmed.关键词
胰腺/神经内分泌肿瘤/磁共振成像/诊断/治疗Key words
pancreas/neuroendocrine neoplasms/magnetic resonance imaging/dagnosis/treatment分类
医药卫生引用本文复制引用
沈威,马周鹏,林观生,陈炳叶,周建军..无功能性胰腺神经内分泌肿瘤的MRI表现及治疗[J].肝胆胰外科杂志,2018,30(1):26-30,5.
