摘要
Abstract
Objective To investigate the related factors of anemia in preterm infants and to provide basis for prevention and treatment of anemia in preterm infants .Methods A total of 230 cases of preterm infants admitted in neonatal wards in Beijing Friendship Hospital from January 2014 to October 2015 and complying with inclusion criteria were selected and retrospectively analyzed . Gestational age ,birth weight ,sex ,hemoglobin at birth and iatrogenic blood collection volume in two weeks /body weight were recorded .Group comparison was made for related factors of anemia in preterm infants .Multiple factor Logistic regression and multivariate linear regression analysis was used in studying risk factors of anemia in preterm infants .Results Among 230 cases of preterm infants ,103 cases had anemia ,and incidence rate of anemia was 44 .8％ .Patients were grouped according to whether they had anemia .Single factor test was performed .Gestational age , birth weight and hemoglobin at birth in anemia group were significantly lower than those in non - anemia group (t value was - 5 .815 , - 2 .823 and - 6 .685 ,respectively ,all P < 0 .05) ,while hospitalization days , iatrogenic blood collection volume in 2 weeks/body weight and ventilator time in anemia group were significantly higher than those in non - anemia group (t value was 5 .263 ,7 .155 and - 6 .663 ,respectively ,all P < 0 .05) .Multiple factor Logistic regression analysis showed that iatrogenic blood collection volume in 2 weeks/body weight ,ventilator use were risk factors (OR value was 1 .446 and 3 .084 ,respectively ,both P < 0 .05) ,while hemoglobin at birth was protective factor (OR =0 .923 ,P < 0 .05) .Multivariate linear regression analysis indicated that hemoglobin at birth and iatrogenic blood collection volume in 2 weeks/body weight were factors affecting severity of anemia ,and hemoglobin at birth and ventilator days were factors affecting occurrence of anemia .Conclusion Properly raising hemoglobin at birth and lowering blood collection volume at 2 weeks after birth are important for reducing occurrence of anemia and its severity in preterm infants .Ventilator and hospitalization days are important factors of anemia in preterm infants .Prevention of unnecessary use of ventilator and shortening of hospital stay are helpful for reducing occurrence of anemia .关键词
贫血/早产儿/胎龄/医源性采血/体重/出生体重/影响因素分析Key words
anemia/premature infants/gestational age/iatrogenic blood collection/body weight/birth weight/analysis of influencing factors分类
医药卫生
