摘要
Abstract
Objective To investigate the risk factors and clinical features of severe preeclampsia (PE) complicated with multiple organ dysfunction syndrome (MODS ) .Methods The clinical data of 80 patients with severe PE were retrospectively analyzed , including 52 cases of severe PE in control group and 28 cases of severe PE complicated with MODS in MODS group .Univariate Logistic regression analysis was performed to find the risk factors ,and two groups were compared in terms of liver function ,renal function ,coagulation function and other laboratory indexes .Results Junior high school and below ,without antenatal examiantion or no periodic inspection ,combined with chronic hypertension were the risk factors of severe PE complicated with MODS (χ2 value was 5 .07 ,5 .04 and 6 .25 ,respectively ,all P < 0 .05) ,while high school and above as well as regular examination were protective factors (χ2 value was 5 .07 and 5 .04 ,respectively ,both P < 0 .05) .The levels of ALT ,AST ,total bilirubin ,SCr and uric acid in MODS group were significantly higher than those in the control group ,and the number of blood platelet was significantly lower than that of the control group (t value was 5 .00 ,6 .04 ,6 .80 ,13 .60 ,9 .90 and 12 .89 ,respectively ,all P < 0 .05) .The risks of placental abruption ,postpartum hemorrhage ,perinatal fetal distress and death in MODS group were significantly higher than those in the control group (χ2 value was 4 .48 ,0 .47 ,6 .04 and 4 .47 ,respectively ,all P < 0 .05) .Conclusion Combined with chronic hypertension can significantly increase the risk of severe PE complicated with MODS .Strengthening health care during pregnancy and regular supervising of antenatal examination are of great significance to prevent the occurrence of MODS and improve pregnancy outcomes .关键词
重度子痫前期/多器官功能障碍综合征/危险因素/临床特点Key words
severe preeclampsia/multiple organ dysfunction syndrome (MODS)/risk factors/clinical features分类
医药卫生
