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固肠胶囊联合匹维溴铵治疗老年腹泻型肠易激综合征临床观察

王红 陈德友 李莉 徐晨霞 陈明欣 刘宝山

河南中医2017,Vol.37Issue(12):2148-2150,3.
河南中医2017,Vol.37Issue(12):2148-2150,3.DOI:10.16367/j.issn.1003-5028.2017.12.0737

固肠胶囊联合匹维溴铵治疗老年腹泻型肠易激综合征临床观察

Clinical Observation of Senile Diarrhea-Predominant Irritable Bowel Syndrome Treated with Intestine-Consolidating Capsule Combined with Pinaverium Bromide

王红 1陈德友 2李莉 3徐晨霞 3陈明欣 3刘宝山1

作者信息

  • 1. 天津医科大学总医院,天津300052
  • 2. 天津中医药大学,天津300193
  • 3. 天津中新药业集团股份有限公司达仁堂制药厂,天津300142
  • 折叠

摘要

Abstract

Objective:To observe the clinical effects of Intestine-Consolidating Capsule combined with Pinaverium Bromide on senile diarrhea-predomiuant irritable bowel syndrome (D-IBS).Methods:Totally 58 patients with senile D-IBS treated in this hospital between December 2013 and December 2015 were randomized into research group and control group,29 cases in each group.There was 1 case in research group and 2 cases in control group withdrew.Control group were given Pinaverium Bromide while research group were given Intestine-Consolidating Capsule combined with Pinaverium Bromide for the treatment.The frequency of defecation,score of Bristol,changes of the scores of gastrointestinal symptoms and IBS-QOL were observed.And the clincal effects of the two groups were compared.Results:The scores of defecation frequency,Bristol and IBS-QOL declined in both groups;research group were superior to control group (P < 0.05).The effective rate was 96.43% in research group and 74.08% in control group;the difference had statistical significance (P < 0.05).The scores of BS-QOL in research group were superior to those in control group (P < 0.05 or P < 0.01).Conclusion:Intestine-Consolidating Capsule combined with Pinaverium Bromide has significant therapeutic effects on senile D-IBS,which can improve the clinial symptoms,relieve the bad mood and enhance quality of life of the patients.

关键词

腹泻型肠易激综合征/固肠胶囊/匹维溴铵

Key words

diarrhea-predominant irritable bowel syndrome (D-IBS)/Intestine-Consolidating Capsule/Pinaverium Bromide

分类

医药卫生

引用本文复制引用

王红,陈德友,李莉,徐晨霞,陈明欣,刘宝山..固肠胶囊联合匹维溴铵治疗老年腹泻型肠易激综合征临床观察[J].河南中医,2017,37(12):2148-2150,3.

基金项目

天津医科大学总医院、天津中新药业达仁堂制药厂合作项目 ()

河南中医

1003-5028

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