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白芍络石方治疗脑梗死后痉挛性瘫痪临床观察

谢乐 伍大华 方锐 张发友 李红梅 周慎

湖南中医药大学学报2018,Vol.38Issue(1):77-81,5.
湖南中医药大学学报2018,Vol.38Issue(1):77-81,5.DOI:10.3969/j.issn.1674-070X.2017.01.020

白芍络石方治疗脑梗死后痉挛性瘫痪临床观察

Effect of Baishao Luoshi Decoction on Spasticity after Ischemic Stroke

谢乐 1伍大华 1方锐 2张发友 3李红梅 3周慎1

作者信息

  • 1. 湖南省中医药研究院附属医院脑病科,湖南 长沙 410006
  • 2. 杭州师范大学医学院,浙江 杭州 310018
  • 3. 湖南中医药大学研究生院,湖南 长沙 410208
  • 折叠

摘要

Abstract

Objective To evaluate the clinical efficacy and security of Baishaoluoshi decoction in treating spasticity after ischemic stroke. Methods 60 patients with post-stroke spasticity were randomly divided into Chinese medicine group (Baishao Luoshi decoction) and control group. The control group was received conventional therapy for 4 weeks, and the Chinese medicine group were treated with Baishao Luoshi decoction for 4 weeks on the basis of conventional therapy. Before treatment, after treatment for 2 weeks and 4 weeks, the myodynamia was evaluated by Robert Lovett's method, the muscle tension of the upper limb was evaluated by Modified Ashworth score (MAS), the muscle tension of the lower limb was evaluated by Compopsite Spasticity Scale (CSS), the neurological deficit symptoms were evaluated by National Institute of Health stroke scale (NIHSS), and the daily living ability was evaluated by Modified Barther Index (MBI). The adverse reaction after intervention was observed. Results After treatment for 2 weeks, the improvement of myodynamia of upper and lower limbs and muscle tension of the upper limb in Chinese Medicine group was better than that in the control group (P<0.05). After treatment for 4 weeks, the improvement of the myodynamia of lower limbs, MBI, and NIHSS were superior to that in the control group (P<0.05). In addition, there was no negative effects of blood routine, liver and kidney functions during treatment.Conclusion Baishao Luoshi decoction can enhance the motor function, ameliorate the spasticity of upper limb, improve the daily living ability in post-stroke spasticity patients, and with a reliable security.

关键词

脑梗死/痉挛性瘫痪/白芍络石方/临床研究

Key words

cerebral infarction/spastic paralysis/ischemic stroke/Baishao Luoshi decoction/clinical efficacy

分类

医药卫生

引用本文复制引用

谢乐,伍大华,方锐,张发友,李红梅,周慎..白芍络石方治疗脑梗死后痉挛性瘫痪临床观察[J].湖南中医药大学学报,2018,38(1):77-81,5.

基金项目

2016年湖南省中医药管理局重点项目(201608). (201608)

湖南中医药大学学报

OACSTPCD

1674-070X

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