实用临床医药杂志2017，Vol.21Issue(24)：6-9,4.DOI:10.7619/jcmp.201724002
不同类型肺腺癌患者高分辨CT表现及病理学分析
High-resolution CT manifestation and pathological analysis of different types of lung adenocarcinoma
摘要
Abstract
Objective To study the high-resolution CT manifestation (HRCT) and pathological analysis of different types of lung adenocarcinoma.Methods The HRCT imaging data of 120 patients with lung adenocarcinoma admitted into our hospital were retrospectively analyzed.According to CT detection results,they were divided into preinvasive group (n =36),micro invasive adenocarcinoma (MIA) (n =44),invasive adenocarcinoma (IAC) (n =40).All the patients were confirmed by surgery pathology and their CT detection image were achieved in 2 weeks before surgery.All the patients received united imaging uCT_S-160 image examination,and patients received pathology diagnosis,the paraffin embedding and HE staining pathological section were reviewed by two senior pathologists,and difficult types of pathology can be decided by two doctors after discussion.The position of lesions,pathological results of lung adenocarcinoma in three groups were observed.The maximum lesion diameter of the atypical adenocarcinoma hyperplasia (AAH),adenocarcinoma in situ (AIS) in preinvasive group were compared,and receiver operating characteristic curve (ROC) was drew.Results The focus of lung adenocarcinoma of preinvasive group tended to occur in superior lobe of right lung and superior lobe of left lung,MIA focus in superior lobe of right lung,inferior lobe of right lung and superior lobe of left lung,IAC focus in superior lobe of right lung,inferior lobe of right lung and superior lobe of left lung.There was no statistical difference in the position of lesions of lung adenocarcinoma among three groups (P ＞ 0.05).The pathological diagnosis showed that the lesion of lung adenocarcinoma of three groups performed as non-mucinous type.The maximum diameter of AAH lesion was lower than AIS (P ＜ 0.05);The ROC curve showed that area under curve (AUC) was 0.915,best threshold value of AAH and AIS was-687 HU,sensitivity was 91.50％,specificity was 94.82％.Conclusion HRCT for detecting lung adenocarcinoma can predict new pathological types and has higher sensitivity and specificity,which has high diagnostic value in AAH detection.The HRCT manifestations of different types of lung adenocarcinoma have certain differences,but these manifestations were not obvious,the focus tend to occur in superior lobe of right lung and superior lobe of left lung,and the pathological analysis performs as non-mucinous type.关键词
肺腺癌/高分辨CT表现/病理学Key words
lung adenocarcinoma/high-resolution CT manifestation/pathology分类
医药卫生引用本文复制引用
涂毅,梁佐堂..不同类型肺腺癌患者高分辨CT表现及病理学分析[J].实用临床医药杂志,2017,21(24):6-9,4.基金项目
湖北省卫计委面上项目(JX62305) （JX62305）
