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PDCD4与MMP-7在胃癌组织中的表达及临床意义OA

Expression and clinical significance of PDCD4 and MMP-7 protein in human gastric carcinoma

中文摘要英文摘要

目的 探讨PDCD4和MMP-7在胃癌组织中的表达及其与临床病理特征的关系.方法 选择手术切除的胃癌组织标本70例,采用免疫组织化学SP法检测70例胃腺癌及癌旁组织的PDCD4和MMP-7的表达水平,探讨其与临床病理学参数的关系.结果 在胃癌组织中MMP-7呈高表达,显著高于对照组(78.6% vs.22.9%,P<0.05),而PDCD4呈低表达,显著低于对照组(31.4% vs.75.7%,P<0.05);PDCD4和MMP-7表达均与淋巴结…查看全部>>

Objective To investigate the expression and significance of PDCD4 and MMP-7 in human gastric carcinoma (GC) tissues and to analyze their association with clinical pathological characteristics in GC patients.Methods Immunohistochemical staining SP was used to detect the expression of PDCD4 and MMP-7 protein in gastric cancer specimens and para-carcinoma tissue in 70 cases,and the relationship with clinical pathological characteristics were analyzed.Results Th…查看全部>>

奚剑波;汤建军;法镇中;闵震宇

江苏大学附属武进医院普外科,江苏常州,213002江苏大学附属武进医院普外科,江苏常州,213002江苏大学附属武进医院普外科,江苏常州,213002江苏大学附属武进医院普外科,江苏常州,213002

医药卫生

基质金属蛋白酶-7程序性细胞死亡因子4胃癌

matrix metalloproteinases-7programmed cell death 4gastric cancer

《实用临床医药杂志》 2017 (24)

19-22,4

10.7619/jcmp.201724006

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