临床误诊误治2018，Vol.31Issue(1)：9-12,4.DOI:10.3969/j.issn.1002-3429.2018.01.003
p-ANCA相关性肥厚性硬脑膜炎误诊病例分析并文献复习
Analysis of Misdiagnosed Cases of Peripheral Antineutrophil Cytoplasmic Antibody Associated Hypertrophic Cranial Meningitis and Literature Review
王占奎 1潘文萍 1侯岩峰 1王秀花 1王庆1
作者信息
- 1. 250014 济南,山东省千佛山医院风湿免疫科
- 折叠
摘要
Abstract
Objective To explore the clinical characteristics, diagnosis, misdiagnosis reasons and preventive meas-ures for the perinuclear antineutrophil cytoplasmic antibody ( p-ANCA) associated hypertrophic pachymeningitis. Methods A retrospective study was performed for 1 case of p-ANCA associated hypertrophic pachymeningitis which was misdiagnosised as systemic vasculitis and headache, and reviewed the relevant literature. Results In this case, the patient was complaining of pain in the legs gastrocnemius, eye conjunctival congestion for more than 2 years and recurrent headaches for 6 months, with positive p-ANCA. It was be repeated treatment as systemic vasculitis and headache. Eventually, it was diagnosed with p-ANCA associated hypertrophic pachymeningitis after Brain magnetic resonance imaging ( MRI) . The treatment of intrathecal methotrexate and dexamethasone effectively relieved headache symptoms in patients. Conclusion The patients with recurrent headaches should be checked the p-ANCA. Head MRI enhancement scan is helpful for diagnosis of p-ANCA associated hyper-trophic pachymeningitis after excluded the diagnosis of ANCA associated vasculitis. It can decrease or avoid misdiagnosis and mistreatment.关键词
硬脑膜炎/抗体,抗中性白细胞胞质/误诊/系统性血管炎Key words
Pachymeningitis/Antibodies/antineutrophil cytoplasmic/Misdiagnosis/Systemic vasculitis分类
医药卫生引用本文复制引用
王占奎,潘文萍,侯岩峰,王秀花,王庆..p-ANCA相关性肥厚性硬脑膜炎误诊病例分析并文献复习[J].临床误诊误治,2018,31(1):9-12,4.
