上海针灸杂志2018，Vol.37Issue(1)：37-41,5.DOI:10.13460/j.issn.1005-0957.2018.01.0037
针刺对功能性消化不良患者心理因素及血清Ghrelin水平的影响
Effect of Acupuncture on Psychological Factors and Serum Ghrelin Levels in Patients with Functional Dyspepsia
张卫 1陈一2
作者信息
- 1. 上海市闵行区梅陇社区卫生服务中心,上海 201104
- 2. 复旦大学附属华东医院,上海 200040
- 折叠
摘要
Abstract
Objective To investigate the effect of acupuncture on the mental health score and serum ghrelin levels in patients with functional dyspepsia (FD).Methods Sixty-eight FD patients were randomized to treatment and control groups, 34 cases each. The treatment group received acupuncture and the control group took domperidone tablets orally. The TCM symptom score and the Symptom Checklist-90 (SCL-90) subscores were recorded and serum ghrelin levels were measured in the two groups before and after treatment.Results There were statistically significant pre-/post- treatment differences in the TCM symptom score and serum ghrelin level in the two groups (P<0.05). There was a statistically significant post-treatment difference in the TCM symptom score between the treatment and control groups (P<0.05). There were statistically significant pre-/post-treatment differences in the SCL-90 somatization, obsessive- compulsive disorder, interpersonal sensitivity, depression, anxiety and psychotic factor subscores in the treatment group (P<0.05). There was a statistically significant pre-/post-treatment difference in the somatization subscore in the control group (P<0.05). There were statistically significant post-treatment differences in the interpersonal sensitivity, depression and anxiety subscores between the treatment and control groups (P<0.05). In FD patients there was a negative correlation of the ghrelin level with the SCL-90 somatization, obsessive-compulsive disorder, interpersonal sensitivity, depression and anxiety subscores (P<0.05).Conclusions Acupuncture can reduce the clinical symptomsand psychological problems in FD patients. Its mechanism of action may be related to raising serum ghrelin levels.关键词
针刺疗法/消化不良/胃促生长素/症状自评量表/电针Key words
Acupuncture therapy/Dyspepsia/Ghrelin/Symptom Checklist-90/Electroacupuncture分类
医药卫生引用本文复制引用
张卫,陈一..针刺对功能性消化不良患者心理因素及血清Ghrelin水平的影响[J].上海针灸杂志,2018,37(1):37-41,5.
