兽类学报2018，Vol.38Issue(1)：56-65,10.DOI:10.16829/j.slxb.150148
母体密度应激与球虫感染对子代根田鼠免疫力的影响
Effects of maternal density stress and coccidiosis infection on immunity in root vole offsprings
摘要
Abstract
The immune function is one of the most important factors to influence animals fitness.As it is a crucial way to defend against bacterial pathogens such as viruses,the immune system plays a key role in animal's survival.Both population density and parasitization are known to deteriorate individuals' immune function.This experiment using 2 × 2 factorial experiment design to measure the indexes of four treatments (maternal density stress + coccidian infection,not maternal density stress + not coccidian infection,maternal density stress + not coccidian infection,not maternal density stress + coccidian infection),including the fecal corticosterone metabolite (FCM),coccidian infection rate,blood parameters,lymphocyte subsets counts (CD4,CD8 counts).The results show that the density-induced maternal stress can significantly reduce the number of CD4,rate of CD4/CD8,Lymphocytes,Eosinophils,white cell.The effects were further deteriorated when maternally stressed offspring infected with coccidian.Our results showed that the interaction of density-induced maternal stress and coccidian infection has negatively synergistic effect on the immune of root vole.关键词
根田鼠/母体应激/球虫/淋巴细胞亚型Key words
Coccidian/Lymphocyte subsets/Maternal stress/Root voles分类
生物科学引用本文复制引用
张鑫,杨彦宾,堵守杨,曹伊凡,周华坤,边疆晖..母体密度应激与球虫感染对子代根田鼠免疫力的影响[J].兽类学报,2018,38(1):56-65,10.基金项目
国家自然科学基金(31570421) （31570421）
国家重点研发计划项目(2016YFC0501902) （2016YFC0501902）
