生物加工过程2018，Vol.16Issue(1)：1-11,11.DOI:10.3969/j.issn.1672-3678.2018.01.001
代谢工程技术方法研究进展
Advance in metabolic engineering technologies and methods
摘要
Abstract
Metabolic engineering is important to build a microbial cell factory.In the past 20 years,metabolic engineering has been widely used to produce high value-added bioactive substances and bulk chemicals, greatly promoted the development of pharmaceutical,energy and environment. In recent years,with the development of related disciplines such as synthetic biology,molecular biology and computer science,metabolic engineering has presented many new developments in analyzing metabolic pathways,improving strain performance and enzyme co-localizing expression.This paper reviews the research and application of those technologies.关键词
代谢工程/合成生物学/代谢网络分析/途径酶共定位Key words
metabolic engineering/synthetic biology/analysis of metabolic pathways/enzyme co-localization分类
生物科学引用本文复制引用
杨祖明,李炳志..代谢工程技术方法研究进展[J].生物加工过程,2018,16(1):1-11,11.基金项目
国家自然科学基金(21622605) （21622605）
天津市科技计划(13RCGFSY19800)) （13RCGFSY19800）
