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酵母细胞工厂生产脂肪酸及其衍生物

高教琪 段兴鹏 周雍进

生物加工过程2018,Vol.16Issue(1):19-30,12.
生物加工过程2018,Vol.16Issue(1):19-30,12.DOI:10.3969/j.issn.1672-3678.2018.01.003

酵母细胞工厂生产脂肪酸及其衍生物

Production of fatty acids and their derivatives by yeast cell factories

高教琪 1段兴鹏 1周雍进1

作者信息

  • 1. 中国科学院 大连化学物理研究所 生物技术研究部,辽宁 大连 116023
  • 折叠

摘要

Abstract

Fatty acids and their derivatives have wide applications in alleviating energy crisis and environmental stresses as advanced fuels. Production of fatty acids and their derivatives by microbes has always been regarded as a renewable and environmental-friendly solution.With the deeper investigation in yeasts and the genetic manipulation, yeast cell factories have become a good platform to produce fatty acids and their derivatives, facing meanwhile unprecedented opportunities and challenges. Therefore, in this review, we present the progress in constructions of yeast cell factories, especially Saccharomyces cerevisiae,Yarrowia lipolytica,and Rhodosporidium toruloides,to produce fatty acids and their derivatives. On this basis,novel synthetic biology strategies to enhance productivities of target products were proposed.

关键词

酿酒酵母/解脂耶氏酵母/细胞工厂/脂肪酸/合成生物学

Key words

Saccharomyces cerevisiae/Yarrowia lipolytica/cell factories/fatty acids/synthetic biology

分类

生物科学

引用本文复制引用

高教琪,段兴鹏,周雍进..酵母细胞工厂生产脂肪酸及其衍生物[J].生物加工过程,2018,16(1):19-30,12.

基金项目

中国科学院大连化学物理研究所创新基金 ()

生物加工过程

OACSTPCD

1672-3678

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