生物加工过程2018，Vol.16Issue(1)：31-37,7.DOI:10.3969/j.issn.1672-3678.2018.01.004
多糖的氧化改性及在生物医药领域的应用
Preparation and biomedical applications of oxidized polysaccharides
摘要
Abstract
Oxidation is one of the simplest and widely used methods in chemical modification of polysaccharides.In the process of oxidation,hydroxyl groups of polysaccharides molecules are oxidized to aldehyde or carboxyl groups. Oxidized polysaccharides with these groups have many desirable properties and have been widely used in the fields of food,medicine,and chemical engineering. In this review,the mechanisms and conditions of polysaccharides oxidation with different oxidizing agents,including sodium periodate,sodium hypochlorite and hydrogen peroxide are introduced.Then the effects of oxidation on the molecular structure and physicochemical properties of oxidized polysaccharides are described.In addition, we presented in details the application of oxidized polysaccharides as crosslinking, inclusive and antibacterial agents for biomedical materials.关键词
氧化多糖/交联剂/包合物/抗菌剂Key words
oxidized polysaccharides/crosslinking agent/inclusion complex/antibacterial agent分类
生物科学引用本文复制引用
訾娅鑫,雷金凤,徐志朗,李德富,穆畅道..多糖的氧化改性及在生物医药领域的应用[J].生物加工过程,2018,16(1):31-37,7.基金项目
国家自然科学基金(21206098、21276166) （21206098、21276166）
四川大学优秀青年学者科研基金(2015SCU04A34) （2015SCU04A34）
