信阳师范学院学报（自然科学版）2018，Vol.31Issue(1)：145-151,7.DOI:10.3969/j.issn.1003-0972.2018.01.029
EGCG对肿瘤干细胞抑制效应研究进展
Progress in EGCG Functioned on Cancer Stem Cells
摘要
Abstract
(-)-Epigallocatechin-3-gallate (EGCG),a major bioactive constituent in green tea,possesses anti-carcinogenic potential in different tumors.Recent data also showed that EGCG displayed its anti-cancer activity by targeting CSCs.This review focusses on the studies of EGCG functioned on characteristics,including migra-tion and invasion,anti-chemotherapy,self-renewal and tumorigenicity.In addition,signaling pathways,inclu-ding Wnt/β-catenin,Hedgehog,Notch and AKT pathways,involved in these progress were discussed to pro-vide options for cancer and treatment.关键词
EGCG/肿瘤干细胞/自我更新/迁移性/致瘤性/综述Key words
EGCG/cancer stem cells/self-renewal/migratory/tumorigenicity/review分类
医药卫生引用本文复制引用
陈磊,李开鸣,马会景,曾宪思,贾金婧,宋新强..EGCG对肿瘤干细胞抑制效应研究进展[J].信阳师范学院学报（自然科学版）,2018,31(1):145-151,7.基金项目
国家自然科学基金项目(81502312,31600837) （81502312,31600837）
信阳师范学院博士科研启动基金(0201305) （0201305）
