中国病理生理杂志2018，Vol.34Issue(1)：188-192,5.DOI:10.3969/j.issn.1000-4718.2018.01.033
基质蛋白CCN1与肺部疾病的研究进展
Progress on role of CCN1 in pulmonary diseases
摘要
Abstract
Cysteine-rich angiogenic inducer 61(Cyr61/CCN1)is an extracellular matrix-associated signaling protein consisting of 381 amino-acid residues ,which has the regulatory function for a multitude of cellular responses.The pleiotropic effects of CCN 1 on the initiation and resolution of inflammation as well as oncogenesis and development of tumor were reported.According to the numerous data from experimental and clinical studies ,this article provides an overview on CCN1 and summarizes the latest understanding of the role of CCN 1 in pulmonary diseases.关键词
CCN1/急性肺损伤/慢性阻塞性肺病/肺癌Key words
CCN1/Acute lung injury/Chronic obstructive pulmonary disease/Lung cancer分类
医药卫生引用本文复制引用
董年,宋晨剑,裘丹萍,陈成水..基质蛋白CCN1与肺部疾病的研究进展[J].中国病理生理杂志,2018,34(1):188-192,5.基金项目
国家自然科学基金资助项目(No.81270131 （）
No.81770074) （）
