中国耳鼻咽喉颅底外科杂志2017，Vol.23Issue(6)：555-558,4.DOI:10.11798/j.issn.1007-1520.201706012
喉前淋巴结转移对声门型喉癌治疗的指导作用
The guiding role of prelaryngeal lymph node metastasis in the treatment of glottic carcinoma
蔡志良 1林忠豪 1陈缪安 1李聪1
作者信息
- 1. 福建医科大学附属闽东医院宁德市闽东医院耳鼻咽喉头颈外科,福建宁德352000
- 折叠
摘要
Abstract
Objective To investigate the regularity of prelaryngeal lymph node metastasis in glottic carcinoma,in order to provide evidence for improving standard operation of laryngeal carcinoma.Methods Clinical data of 73 patients with glottic carcinoma surgically treated from Jan 2006 to Dec 2015 were analyzed retrospectively.The tumor stage,pathological type,postoperative neck lymph node metastasis,local recurrence and survival time were compared between the patients with early and middle-advanced laryngeal carcinoma,and those with and without prelaryngeal lymph node metastasis.Results In 73 cases of glottic carcinoma,the prelaryngeal lymph node metastasis was found in 4 with a positive rate of 5.47％ (4/73).The patients with laryngeal carcinoma of middle-advanced stages (stage Ⅲ and ⅣV) were more likely to develop cervical lymph node metastasis and prelaryngeal lymph node metastasis than those of early stages (stage Ⅰ and Ⅱ),and the differences were statistically significant (P ＜ 0.05).The differences of both cervical and prelaryngeal lymph node metastases between pathological types of well differentiation and poor to moderate differentiation were statistically insignificant (P ＜ 0.05).Postoperative lymph node metastasis and local recurrence were more likely to occur in laryngeal carcinomas of middleadvanced stage than in those of early stage,and the postoperative lymph node metastasis and local recurrence were also more likely to occur in laryngeal carcinomas with prelaryngeal lymph node metastasis than in those without.The differences were all statistically significant(P ＜ 0.05).The survival time of the patients with prelaryngeal lymph node metastasis was shorter than that of those without,and the difference was statistically significant (P ＜ 0.05).Conclusions With high incidence of prelaryngeal lymph node metastasis in advanced laryngeal carcinoma,these lymph nodes should be dissected routinely.Due to increase of postoperative cervical lymph node metastasis and local recurrence,the prognosis of patients with positive prelaryngeal lymph node metastasis is poor,which indicates the necessity of further treatment after surgery.关键词
肿瘤转移/喉肿瘤/颈廓清术Key words
Tumor metastasis/Laryngeal neoplasm/Neck dissection分类
医药卫生引用本文复制引用
蔡志良,林忠豪,陈缪安,李聪..喉前淋巴结转移对声门型喉癌治疗的指导作用[J].中国耳鼻咽喉颅底外科杂志,2017,23(6):555-558,4.
