中国药业2018，Vol.27Issue(1)：24-27,4.DOI:10.3969/j.issn.1006-4931.2018.01.007
独一味煮散颗粒制备工艺研究
Preparation Technology of Duyiwei Boiled Particles
王永 1王猛 1李向军1
作者信息
- 1. 石家庄以岭药业股份有限公司,河北 石家庄 050035
- 折叠
摘要
Abstract
Objective To establish the preparation method of Duyiwei Boiled Particles. Methods The particle size of Duyiwei Boiled Particles was determined by the moldability and filtration of particles, the preparation process was determined by the method of compre-hensive weighting score with the difficulty of molding, filtration, total flavone content and dry paste yield as the indexes. Results The preparation method was as follows: granulation with Duyiwei powder, added the amount of Duyiwei powder of 30％ water as the binder, and the granules were dried at 65 ℃ for 90 min. Under the same extraction conditions, the total flavonoids extraction rate was 32. 38 mg / g, the paste rate was 27. 30％ , while the traditional slices of flavonoids extraction rate was only 16. 53 mg / g, and the paste rate was 8. 80％ . Conclusion Compared with traditional decoction pieces, Duyiwei Boiled Particles has obvious advantages in extracting effective ingredients and reducing production cost.关键词
独一味煮散颗粒/挤压制粒法/总黄酮/干膏收率/综合加权评分Key words
Duyiwei Boiled Particles/extrusion granulation method/total flavonoids/dry paste yield/comprehensive weighted score分类
化学化工引用本文复制引用
王永,王猛,李向军..独一味煮散颗粒制备工艺研究[J].中国药业,2018,27(1):24-27,4.
