中国药业2018，Vol.27Issue(2)：19-22,4.DOI:10.3969/j.issn.1006-4931.2018.02.005
麦冬化学成分研究
Study on Chemical Constituents of Ophiopogon Japonicus
摘要
Abstract
Objective To investigate the chemical constituents of Ophiopogon japonicus and establish a method of isolation and identification.Methods The chemical compounds were separated by Sp825 macroporous adsorption resin and ODS-C18 chromatographic column from 70％ ethanol extract of Ophiopogon japonicus,and then they were identified.Results With spectroscopic analysis and physical-chemical data determination methods,5 compounds were identified as 3,4-dihydroxy-allylbenzene 4-O-[α- L-rhamnopyranosyl-(1→6)] -β- D-glucopyranoside,borneol 7-O-β- D-glucopyranoside,( 22S)-cholest-5-ene-1β,3β,16β,22-tetraol-1-O-α- L-rhamnopyranosyl-16-O-β- D-glucopyranoside,methyophiopogonanone A,methyophiopogonanone B.Conclusion The method has good separation effect,and the compounds can be identified accurately.In the future,the above 5 compounds can be further studied in order to help Ophiopogon japonicus play a greater role in clinical.关键词
麦冬/化学成分/高异黄酮/苯丙醇苷/龙脑苷/胆甾醇苷Key words
Ophiopogon japonicus/chemical constituents/homoisoflavonoid/phenylpropanoid glycoside/borneol glycoside/cholesterol glycoside分类
医药卫生引用本文复制引用
旷湘楠,朱娜,刘时乔..麦冬化学成分研究[J].中国药业,2018,27(2):19-22,4.基金项目
河北省中医药管理局科研计划项目[2017020] （）
河北中医学院博士科研基金项目[BSZ2017004] （）
河北中医学院"大学生创新创业训练计划"项目[201614432030]. （）
