摘要
Abstract
Objective To investigate the effect of safflower yellow combined with low molecular weight heparin calcium on oxidative stress and nerve function in patients with acute cerebral infarction.Methods Totally 238 patients with acute cerebral infarction admitted to our hospital from January 2015 to November 2016 were selected and divided into the control group and the observation group according to the time of admission,119 cases in each group.The control group were treated with low molecular weight heparin calcium(5000 U per time,once a day),on this basis,the observation group was given intravenous drip of safflower yellow(100 mg per time,once a day).The course of treatment was 14 d.Results The total effective rate of the observation group was significantly better than that of the control group(88.23％ vs.55.46％,P < 0.05).After treatment,the level of Ox-LDL in the observation group was significantly reduced,and the level of GSH-Px was significantly increased,which was significantly higher than those in the control group at the same time point(P < 0.05).After 3,14 d of treatment,the NIHSS score of the observation group was decreased gradually,which was significantly lower than that of the control group at the same time point(P < 0.05).No serious adverse reactions occurred during the treatment in the two groups.Conclusion Safflower yellow combined with low molecular weight heparin calcium in the treatment of acute cerebral infarction has significant effect,which can effectively improve the oxidative stress index level and nerve function,and it is worthy of clinical promotion.关键词
红花黄色素/低分子肝素钙/急性脑梗死/氧化应激/神经功能Key words
safflower yellow/low molecular weight heparin calcium/acute cerebral infarction/oxidative stress/nerve function分类
医药卫生
