摘要
Abstract
Objective To determine factors affecting the surgical difficulty of endoscopic submucosal dissection in patients with colorectal cancer.Methods 70 patients of colorectal cancer treated with endoscopic submucosal dissection in our hospital were analyzed retrospectively.The difficulty of operation was measured using the standard of operation time.The operation time is less than 60min.Patients were categorized as with small difficulty operation (operation time ＜ 60 min) and great difficulty operation (operation time ≥ 60 min).Univariate and logistic regression analysis was performed with sex,age,tumor diameter,lesion site,fibrosis and tumor types of the patients,tumor differentiation and tumor TNM staging as possible predictors associated with operation difficulty.Results In this study,9 patients were difficult to operate,and 61 patients were relatively easy to operate.Unianalysis showed that tumor diameter,lesion location,fibrosis and tumor type were significantly associated with the operation difficulty (P ＜ 0.05).Multivariate Logistic regression analysis showed that tumor diameter,tumor occurring at the left colon,severe fibrosis and lateral developmental tumor were independent risk factors for operation difficulty (P ＜ 0.05).Conclusion The tumor diameter ≥ 40 mm,tumor occurring at the left colon,severe fibrosis,laterally spreading tumor can prolong the operation time and increase the difficulty of operation.Cautions should be made for such patients.关键词
内镜黏膜下剥离术/结直肠癌/手术难度/影响因素Key words
endoscopic submucosal dissection/colorectal cancer/surgical difficulty/influencing factors分类
医药卫生
