南方医科大学学报2018，Vol.38Issue(2)：229-233,5.DOI:10.3969/j.issn.1673-4254.2018.02.18
七氟醚与喉罩在妊娠合并心脏病产妇剖宫产手术中的应用
Application of sevoflurane and laryngeal mask in cesarean section in women with heart disease
摘要
Abstract
Objective To compare the safety of sevoflurane anesthesia with laryngeal mask and tracheal intubation in cesarean section in women with heart disease. Methods Fifty-two pregnant women with heart diseases undergoing cesarean section were randomized into laryngeal mask (LAM) group and tracheal intubation group. In LAM group, 6％sevoflurane was given at the rate of 6 L/min for induction with a maintenance sevoflurane concentration of 3％. In the intubation group, 1.5 mg/kg propofol and 1μg/kg remifentanil were injected intravenously, and after achieving D0 with Narcotrend monitoring, 0.9 mg/kg rocuronium was injected and intubation was performed 1 min later. The systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and heart rate (HR) were recorded in the two groups before anesthesia induction (T0), at intubation or laryngeal mask placement (T1), skin incision (T2), and extubation or laryngeal mask removal (T3). The surgery to fetal birth time, uterine incision to fetal childbirth time, drug discontinuation to awake time, and newborn Apgar scores were also recorded. Sevoflurane consumption and maternal comfort during hospitalization were compared between the two groups. Results In LAM group, HR and MBP at T1 and T3 were significantly lower than those in the intubation group (P<0.05). The drug discontinuation to extubation time and to awaken time were significantly shorter in LAM group than in the intubation group (P<0.05), but the operation time and fetal child birth time were comparable between the two groups (P>0.05). The women in LAM group reported better physical and psychological comforts than those in the intubation group (P<0.05). The neonatal Apgar scores and the scores of health education, satisfaction with hospital environment and service were all similar between the two groups (P>0.05). Conclusion Sevoflurane anesthesia with laryngeal mask can achieve satisfactory anesthetic effects in cesarean section in women with heart disease.关键词
妊娠合并心脏病/七氟醚/喉罩Key words
pregnancy with heart disease/sevoflurane/laryngeal mask引用本文复制引用
王志鹏,马珏,王晟,郁丽娜,韦锦锋,徐金东..七氟醚与喉罩在妊娠合并心脏病产妇剖宫产手术中的应用[J].南方医科大学学报,2018,38(2):229-233,5.基金项目
贝朗麻醉科学研究基金(院内编号:Z022016001) （院内编号:Z022016001）
