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牙源性干细胞储存和临床应用的研究进展

叶青松 王晓燕

口腔疾病防治2018,Vol.26Issue(1):15-25,11.
口腔疾病防治2018,Vol.26Issue(1):15-25,11.DOI:10.12016/j.issn.2096-1456.2018.01.004

牙源性干细胞储存和临床应用的研究进展

Progress in storage and clinical application of dental stem cells

叶青松 1王晓燕2

作者信息

  • 1. 澳大利亚昆士兰大学牙学院,澳大利亚布里斯班 4006
  • 2. 温州医科大学口腔医学院干细胞与组织工程研究所,浙江温州 325035
  • 折叠

摘要

Abstract

Derived from the neural crest, dental stem cells (DSCs) are a population of cells with the characteristics of mesenchymal stem-ness, which under certain appropriate conditions can differentiate into multiple cells such as os-teocytes, chondrocytes, hepatocyte and neuronal-like cells. DSCs are consist of odontogenic stem cells mainly include dental pulp stem cells, periodontal ligament stem cells, stem cells from deciduous teeth, stem cells from apical papilla, as well as dental follicle progenitor cells. DSCs have been widely used in the field of regenerative medicine research and preclinical research, including nervous system diseases, oral diseases, immune diseases, heart and lung diseases, etc. This review will focus on the storage of DSCs and current translational and clinical studies regarding DSCs in tissue regeneration.

关键词

牙源性/干细胞/再生医学/临床前研究/临床试验/干细胞储存/组织工程

Key words

Odontogenic/Stem cells/Regenerative medicine/Translational research/Clinical trials/Stem cells Banking/Tissue engineering

分类

医药卫生

引用本文复制引用

叶青松,王晓燕..牙源性干细胞储存和临床应用的研究进展[J].口腔疾病防治,2018,26(1):15-25,11.

基金项目

澳中科学研究基金(ACSRF14) (ACSRF14)

第十批中组部国家千人计划青年人才项目 ()

口腔疾病防治

OACSTPCD

1006-5245

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