口腔疾病防治2018，Vol.26Issue(1)：43-47,5.DOI:10.12016/j.issn.2096-1456.2018.01.008
糖尿病患者口腔颌面部间隙感染临床及细菌学分析
The clinical and bacteriological analysis of the diabetic with oral and maxillofacial space infections
摘要
Abstract
Objective To analyze the clinical characteristics of oral and maxillofacial space infection between the diabetic and non-diabetic patients and to explore the common pathogenic bacteria and antibiotic sensitivity of diabetic patients, to guide the clinical medication. Methods A retrospective study was conducted on 61 patients who received treatment in Qingdao municipal hospital affiliated to Qingdao university, between December 2014 and December 2016 with Oral and maxillofacial space infection. The 61 patients were divided into diabetic group and non-diabetic group. The research contented the patients'age, sex, source of infection, pathogenic bacteria, antibacterial drugs sensitivity, fast-ing blood glucose levels, white blood cell total and neutrophils percentage, and days of hospitalization. T test and chi-square test in SASS.19.0 software was used. Results In the 2 groups of patients, the most common etiological factor was odontogenic infection;the most easiest affected space was submandibular space. The most common pathogenic bac-teria were streptococcus. Vancomycin was the most sensitive drug, then levofloxacin and cefotaxime. In addition, the dia-betes patients ' age, fasting blood glucose levels and hospitalization days were significantly higher than non-diabetic pa-tients '. Conclusion For the diabetic patients with maxillofacial space infection, levofloxacin and cefotaxime was first used for the conservative treatments when the results of the bacterial culture and drug susceptibility test are not ob-tained. Meanwhile, according to the oral and maxillofacial anatomy, combination of anti-anaerobic agents such as Tinida-zole is also suggested. But the final situation of medication is based on the result of the drug susceptibility test.关键词
糖尿病/口腔/颌面部/间隙感染/病原菌/抗菌药物敏感性Key words
Diabetes/Oral/Maxillofacial/Space infection/Pathogenic bacteria/Sensitivity to antimicrobi-al drugs分类
医药卫生引用本文复制引用
于珊珊,李涛,董刚,李凤梅,郑建金..糖尿病患者口腔颌面部间隙感染临床及细菌学分析[J].口腔疾病防治,2018,26(1):43-47,5.基金项目
青岛市科技计划项目(15-9-2-79-nsh) （15-9-2-79-nsh）
