国际口腔医学杂志2017，Vol.44Issue(6)：628-635,8.DOI:10.7518/gjkq.2017.06.002
肠道微生物调控骨代谢的研究进展
Research progress on gut microbiota regulating bone metabolism
摘要
Abstract
Heterogeneous microbiota dwells in the human gastrointestinal tract,and the maintenance of gut microbiota homeostasis plays an important role in normal host metabolism.With advancement in studies on human microbial communities,the effects of gut microbiota on bone metabolism have been extensively investigated.This review summarizes the research progress on the association between gut microbiome and bone metabolism and focuses on the relationship between gut microbiota and bone fitness,the potential mechanisms of mutual interactions,and the relationship between intestinal microbiota and alveolar bones.Research advancement in this field not only enhances our understanding of the etiological role of gut microbiota in bone metabolism-related diseases but also possibly provides a novel approach for the management of bone diseases involving the microbiota.关键词
肠道/微生物群落/骨代谢/牙槽骨/牙周炎Key words
gut/microbiota/bone metabolism/alveolar bone/periodontitis分类
生物科学引用本文复制引用
吴琪,刘程程,郑黎薇,李继遥,周学东,徐欣..肠道微生物调控骨代谢的研究进展[J].国际口腔医学杂志,2017,44(6):628-635,8.基金项目
国家自然科学基金(81430011,81371135) （81430011,81371135）
四川大学优秀青年学者基金(2015SCU04A16)This study was supported by National Natural Science Foundation of China(81430011,81371135) and Scientific Research Foundation for Young Investigators,Sichuan University,China(2015SCU04A16). （2015SCU04A16）
