海南医学院学报2018，Vol.24Issue(1)：26-29,4.DOI:10.13210/j.cnki.jhmu.20171222.010
细菌性血流感染早期血培养阳性和阴性患者血清炎症反应介质差异的比较
Differences in serum inflammatory mediators between early blood culture positive and nega-tive patients with bacterial bloodstream infection
摘要
Abstract
Objective:To study the differences in serum inflammatory mediators in early blood culture positive and neg-ative patients with bacterial bloodstream infection .Methods:Patients who were hospitalized due to suspected bacterial blood-stream infection between December 2015 and September 2017 were divided into positive group and negative group according to the results of blood culture ,and healthy volunteers who underwent medical examination during the same period were selected as control group .Peripheral blood specimens were collected from patients with suspected bacteremia on admission ,the periph-eral blood specimens were collected from the control group of volunteers during physical examination ,and the levels of pro-in-flammatory cytokines ,anti-inflammatory cytokines ,adhesion factors and chemokines were determined .Results:Serum PCT , CRP ,IL-6 ,IL-17 ,IL-23 ,IL-4 ,IL-10 ,IL-13 ,sTM ,ICAM-1 ,VCAM-1 ,EOTAXIN-3 and MCP-1 levels of positive group and negative group were significantly higher than those of control group ,and serum PCT ,CRP ,IL-6 ,IL-17 ,IL-23 ,IL-4 ,IL-10 ,IL-13 ,sTM ,ICAM-1 ,VCAM-1 ,EOTAXIN-3 and MCP-1 levels of positive group were significantly higher than those of negative group .Conclusion:Detection of serum inflammatory mediators can early predict the bacterial bloodstream infection .关键词
细菌性血流感染/血培养/炎症介质Key words
bacterial bloodstream infection/blood culture/inflammatory mediators分类
医药卫生引用本文复制引用
杨红云..细菌性血流感染早期血培养阳性和阴性患者血清炎症反应介质差异的比较[J].海南医学院学报,2018,24(1):26-29,4.基金项目
It is supported by Key Project of Education Department of Hubei Province (D20131308). 湖北省教育厅重点项目(D20131308) （D20131308）
