海南医学院学报2018，Vol.24Issue(1)：94-96,100,4.DOI:10.13210/j.cnki.jhmu.20171227.004
血清肿瘤标志物CA153、CA125、CA72-4及FIB、IL-6水平用于卵巢癌检测的临床意义
Clinical significance of serum tumor markers CA 153 ,CA125 ,CA72-4 and FIB ,IL-6 levels detection in ovarian cancer
摘要
Abstract
Objective:To investigate the clinical significance of serum tumor markers CA 153 ,CA125 ,CA72-4 and FIB ,IL-6 levels in the detection of ovarian cancer .Method :40 patients with ovarian carcinoma treated in our hospital from September 2015 to June 2017 were selected as the ovarian cancer group ;40 patients with benign ovarian tumors in the same pe-riod were selected as the benign ovarian tumor group ;40 healthy subjects were selected as the control group .The levels of tumor markers CA153 ,CA125 ,CA72-4 and FIB ,IL-6 were compared between the three groups .Results:The CA153 , CA125 ,CA72-4 and FIB ,IL-6 levels of the ovarian cancer group were significantly higher than that in benign ovarian tumor group and the control group (P<00.5);these levels in the benign ovarian tumor group was not significantly different from those in the control group (P>00.5) .With the increasement of clinical phase ,the levels of CA153 ,CA125 and CA72-4 in pa-tients with ovarian cancer were gradually increased ,and the levels in phase Ⅲ and Ⅳ were significantly higher than those in phase Ⅱ and in phase Ⅰ (P<00.5);and the CA125 in phase Ⅱ was significantly higher than that in phase I .The levels of FIB and IL-6 in phase Ⅱ and in phase Ⅲ ,Ⅳ were significantly higher than those in phase Ⅰ (P<00.5);the IL-6 level in phase Ⅲ , Ⅳ was significantly higher than that in phase Ⅱ (P<00.5) .Conclusion:Serum tumor markers CA153 ,CA125 ,CA72-4 and FIB ,IL-6 levels for ovarian cancer detection can be helpful for clinical diagnosis and worthy of promotion .关键词
CA153/CA125/CA72-4/FIB/IL-6/卵巢癌检测Key words
CA153/CA125/CA72-4/FIB/IL-6/ovarian cancer detection分类
医药卫生引用本文复制引用
刘忠杰,赵宁,宋永祯,李桂芬..血清肿瘤标志物CA153、CA125、CA72-4及FIB、IL-6水平用于卵巢癌检测的临床意义[J].海南医学院学报,2018,24(1):94-96,100,4.基金项目
It is supported by Natural Science Foundation Project of Hebei Province (H2015142017). 河北省自然科学基金项目(H2015142017) （H2015142017）
