解放军医学杂志2017，Vol.42Issue(12)：1078-1082,5.DOI:10.11855/j.issn.0577-7402.2017.12.10
冠心病患者合并肾动脉狭窄的危险因素分析
Relative risk factors of patients with coronary heart disease combined with renal artery stenosis
摘要
Abstract
Objective To investigate the risk factors of atherosclerotic renal artery stenosis (ARAS) in patients with coronary heart disease.Method Six hundred and seventy-seven patients with suspected or certainly diagnosed as coronary heart disease consecutively underwent selective coronary angiography and non-selective renal artery angiography during May to Sep.2016 in the Department of Cardiology of General Hospital of Shenyang Military Region.According to the degree of renal artery stenosis,the subjects were divided into renal artery normal group,renal artery slight stenosis group (renal artery stenosis ＜50％) and renal artery obvious stenosis group (renal artery stenosis ＞50％).Both univariate and multivariate logistic regression analysis were used to study the independent risk predictors of ARAS.Results By analysis of clinical data,it was found that age,systolic blood pressure,pulse pressure and creatinine level were higher in patients with different degrees of renal artery stenosis than in renal artery normal group (P＜0.05).There were significant differences in different degrees of renal artery stenosis groups in female,hypertension,left main coronary artery (P＜0.05).The proportion of coronary double vessel lesions was higher in renal artery slight stenosis group than in renal artery normal group (P＜0.05).Age,pulse pressure and creatinine level were significantly higher in renal artery obvious stenosis group than in the other two groups (P＜0.05).Peripheral vascular disease,left main coronary artery disease,single coronary artery and three vessel disease were significantly higher than that in other two groups (P＜0.05).The incidence of renal artery obvious stenosis was 18.9％ in patients with renal artery obvious stenosis,and was 16.7％ in renal arteries slight stenosis group.By univariate and multivariate Logistic regression analysis,age,female,peripheral vascular disease,and multivessel coronary artery disease were independent risk factors for ARAS.Conclusion Renal artery angiography should be routinely performed for patients with coronary artery disease undergoing coronary angiography to identify ARAS,especially for elderly and female patients associated with peripheral vascular disease.关键词
肾动脉狭窄/动脉粥样硬化/危险因素/冠状动脉疾病Key words
renal artery stenosis/atherosclerosis/risk factors/coronary heart disease分类
医药卫生引用本文复制引用
傅文霞,王效增,张磊,姚莹,刘丽稳,荆全民..冠心病患者合并肾动脉狭窄的危险因素分析[J].解放军医学杂志,2017,42(12):1078-1082,5.基金项目
国家临床重点专科军队建设项目(2017) （2017）
This work was supported by the Construction Program of National Clinical Priority Speciality (2017) （2017）
