山东医药2018，Vol.58Issue(1)：16-18,3.DOI:10.3969/j.issn.1002-266X.2018.01.005
血清hs-CRP及VEGF水平对急性心肌梗死经皮冠状动脉介入治疗术后心血管事件的影响
Effects of hs-CRP and VEGF on major adverse cardiovascular events in patients with acute myocardial infarction after percutaneous coronary intervention
摘要
Abstract
Objective To explore effects of serum high-sensitivity C-reactive protein ( hs-CRP) and vascular endo-thelial growth factor (VEGF) on the major adverse cardiovascular events (MACE) in patients with acute myocardial infarc-tion (AMI) after percutaneous coronary intervention (PCI).Methods Totally 116 patients with AMI were treated by PCI.According to the occurrence of MACE after PCI , the patients were divided into the MACE group of 20 cases and non-MACE (NMACE) group of 96 cases.We analyzed the levels of hs-CRP and VEGF in patients before PCI , and at 1 h, 24 h, and 7 d after PCI.Results At 1 h, 24 h, and 7 d after PCI, the serum hs-CRP levels were (5.79 ±1.13), (6.87 ± 1.42), and (3.51 ±0.89) mg/L in the MACE group, and the serum VEGF levels were (167.8 ±49.8), (146.8 ± 43.9), and (121.5 ±29.6) pg/mL, respectively;the serum levels of hs-CRP in the NMACE group were (4.57 ±1.09), (5.38 ±1.21), and (2.67 ±0.58) mg/L, and the serum hs-CRP levels were (145.7 ±40.3), (115.6 ±39.7), and (95.7 ±21.7) pg/mL, respectively.Significant differences were found at different time points between these two groups (all P<0.05).Conclusion The serum hs-CRP and VEGF levels have some clinical value in predicting the occurrence of MACE in patients with AMI after PCI .关键词
急性心肌梗死/经皮冠状动脉介入治疗/C反应蛋白质/血管内皮生长因子Key words
acute myocardial infarction/percutaneous coronary intervention/high-sensitivity C-reactive protein/vas-cular endothelial growth factor分类
医药卫生引用本文复制引用
艾民,颜昌福,夏福纯,周双陆,贺剑..血清hs-CRP及VEGF水平对急性心肌梗死经皮冠状动脉介入治疗术后心血管事件的影响[J].山东医药,2018,58(1):16-18,3.基金项目
四川省医学科研课题(S16046) （S16046）
四川省卫生和计划生育委员会科研课题(150097). （150097）
