天津中医药2018，Vol.35Issue(1)：7-10,4.DOI:10.11656/j.issn.1672-1519.2018.01.03
芪冬颐心口服液对急性心肌梗死患者临床疗效及预后的影响
Effects of Qidong Yixin oral liquid on clinical efficacy and prognosis in patients with acute myocardial infarction
摘要
Abstract
[Objective] To observe the effect Qidong Yixin oral liquid on clinical efficacy and prognosis in patients with acute myocardial infarction. [Methods] A total of 280 patients with acute myocardial infarction were selected from January 2013 to January 2016, these patients were randomly divided into the control group (140) and the treatment group (140). The control group was given routine therapy, and the treatment group was given Qidong Yixin oral liquid for six months on basis of conventional treatment. The clinical efficacy, inflammatory parameters, adverse cardiovascular events incidence and cardiac function after treatment were observed. [Results] After treatment, the total effective rate was 92.9％in the treatment group, which was significantly higher than that in the control group (85.0％), and the difference was statistically significant (P<0.05). Compared with before treatment, the levels of hs-CRP, IL-6 and TNF-αwere significantly decreased in two groups after treatment, and the decreased levels of inflammatory indexes in the treatment group were significantly higher than that in the control group (P<0.05). The incidence of MACE was lower in the treatment group than that in the control group, but the difference was not statistically significant (P>0.05). Compared with before treatment, the cardiac function index including the left ventricular diastolic diameter (LVEDD) and left ventricular systolic diameter (LVESD) were significantly decreased, while the left ventricular ejection fraction (LVFF) was significantly higher after treatment, and the above-mentioned cardiac function index in the treatment group were better than the control group. The difference was statistically significant (P<0.05). [Conclusion] Qidong Yixin oral liquid can significantly improve clinical efficacy in patients with acute myocardial infarction, reduce the inflammation index and improve the prognosis, which is worth further clinical application.关键词
急性心肌梗死/芪冬颐心口服液/疗效/预后Key words
acute myocardial infarction/Qidong Yixin oral liquid/clinical efficacy/prognosis分类
医药卫生引用本文复制引用
靳文学,罗浩..芪冬颐心口服液对急性心肌梗死患者临床疗效及预后的影响[J].天津中医药,2018,35(1):7-10,4.基金项目
国家自然科学基金项目(81300197). （81300197）
