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TTF-1、Ki-67及CK19在甲状腺乳头状癌中的表达及诊断价值

李盖天 陈鹏 徐麟 阎龙 李洪涛 刘宏斌

西北国防医学杂志2017,Vol.38Issue(12):792-795,4.
西北国防医学杂志2017,Vol.38Issue(12):792-795,4.DOI:10.16021/j.cnki.1007-8622.2017.12.006

TTF-1、Ki-67及CK19在甲状腺乳头状癌中的表达及诊断价值

Expression and diagnostic value of TTF-1, Ki-67 and CK19 in thyroid papillary carcinoma

李盖天 1陈鹏 1徐麟 2阎龙 2李洪涛 2刘宏斌2

作者信息

  • 1. 甘肃中医药大学,甘肃兰州 730000
  • 2. 解放军兰州总医院普外科
  • 折叠

摘要

Abstract

Objective:To evaluate the expression and diagnostic value of TTF-1,Ki-67 and CK19 in thyroid papillary carcinoma.Methods:Sixty six patients with thyroid papillary carcinoma and 50 patients with nodular goiter from January to December 2016 in our department were selected,and the expression of TTF-1,Ki-67 and CK19 in the pathdogic tissue were detected by immunohistochemical method.Results:The positive expression rate of TTF-1,Ki-67 and CK19 in patients with thyroid papillary carcinoma were 95.5%,96.9% and 89.7%,significantly higher than those of 88.0%,12.0% and 16.0% in patients with nodular goiter,the difference was statistically significant (P <0.01).Conclusion:TTF-1,Ki-67 and CK19 have application value in the diagnosis of papillary thyroid carcinoma.

关键词

甲状腺乳头状癌/甲状腺转录因子-1/细胞核增殖抗原标记物/细胞角蛋白19/结节性甲状腺肿

Key words

thyroid papillary carcinoma/TTF-1/Ki-67/CK19/nodular goiter

分类

医药卫生

引用本文复制引用

李盖天,陈鹏,徐麟,阎龙,李洪涛,刘宏斌..TTF-1、Ki-67及CK19在甲状腺乳头状癌中的表达及诊断价值[J].西北国防医学杂志,2017,38(12):792-795,4.

西北国防医学杂志

1007-8622

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