烟草科技2017，Vol.50Issue(12)：61-69,9.
GC/MS法同时测定主流烟气中9种芳香胺
Simultaneous determination of nine aromatic amines in mainstream cigarette smoke by GC/MS
摘要
Abstract
To determine nine aromatic amines in mainstream cigarette smoke, a modified vortex-assisted dispersive liquid phase microextraction(LPME)method coupled with gas chromatography-mass spectrometry (GC/MS)was developed by optimizing the main influencing factors of sample pretreatment. The analyzed nine aromatic amines were o-toluidine(o-TOL), m-toluidine(m-TOL), p-toluidine(p-TOL), 2,6-dimethylaniline(2,6-DMA), o-anisidine(o-ASD), 1-naphthylamine(1-NA), 2-naphthylamine(2-NA), 3-aminobiphenyl(3-ABP) and 4-aminobiphenyl(4-ABP). The results indicated that: 1)Using dispersive LPME, the best extraction solvent was toluene with the optimal volume of 1.5 mL, and Na2SO4was chosen as the salting-out reagent. 2)For derivatization, heptafluorobutyric anhydride was selected as derivatization agent with the volume of 5 μL. 3)For d-SPE, the mixture of MgSO4, PSA and C18was employed for cleanup. 4)The limits of detection for the nine aromatic amines ranged from 0.03 to 0.08 ng/cig. The recovery was from 75.0% to 127.3% with the relative standard deviations of 0.2%-9.6%. The developed method features simple sample pretreatment and is suitable for the determination of the nine aromatic amines in mainstream cigarette smoke.关键词
芳香胺/卷烟/主流烟气/分散液相微萃取/气相色谱质谱(GC/MS)Key words
Aromatic amine/Cigarette/Mainstream cigarette smoke/Dispersive liquid phase microextraction/GC/MS分类
轻工纺织引用本文复制引用
邓惠敏,李中皓,边照阳,杨飞,刘珊珊,范子彦,王颖,姜兴益,唐纲岭..GC/MS法同时测定主流烟气中9种芳香胺[J].烟草科技,2017,50(12):61-69,9.基金项目
河南省留学人员与专家服务中心留学人员科研择优资助项目"基于分散液液微萃取的水相模拟物中光引发剂的GC-MS检测方法研究"(502017AS0380) （502017AS0380）
广西中烟工业有限责任公司科技项目"广西中烟卷烟产品履约符合性的研究"(201545000034013). （201545000034013）
