应用化学2018，Vol.35Issue(1)：40-45,6.DOI:10.11944/j.issn.1000-0518.2018.01.170317
一种基于联萘衍生物荧光探针的合成及其对精氨酸的识别
Synthesis of Binol-based Fluorescence Probe and Recognition of Arginine
摘要
Abstract
A kind of fluorescence probe based on (R)-2,2′-dihydroxy-[1,1′-binaphthalene]-3-carboxaldehyde was constructed . The structure was characterized by hydrogen/carbon nuclear magnetic resonance spectroscopy ( 1 H NMR, 13 C NMR ) and mass spectrometry ( MS ) . The results show that the fluorescent probe can detect arginine in a sensitive and highly selective manner with a double response of color and intense fluorescence .The corresponding fluorescence enhancement ratio is in good linear relation with the concentration of arginine (0～30 μmol/L), the correlation coefficient R2 is 0.9914 and the lowest detection limit is 1.3 μmol/L.In addition , the addition of arginine also caused the chiral structure of the probe to deflect, and the changes of binaphthol derivative axial chiral were verified by the changes of the circular dichromatic spectrum .关键词
联萘酚/荧光探针/精氨酸/手性Key words
binaphthol/fluorescence probe/arginine/chirality分类
化学化工引用本文复制引用
刘传涛,肖婷,王芳,陈小强..一种基于联萘衍生物荧光探针的合成及其对精氨酸的识别[J].应用化学,2018,35(1):40-45,6.基金项目
国家自然科学基金项目(21722605,21376117,21406109)、江苏省杰出青年基金项目(BK20140043)和江苏省教育厅自然科学基金项目(14KJA150005)资助 Supported by the National Natural Science Foundation of China(No.21722605, No.21376117, No.21406109), the Jiangsu Natural Science Funds for Distinguished Young Scholars(No.BK20140043), the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (No.14KJA150005) （21722605,21376117,21406109）
