中国感染控制杂志2017，Vol.16Issue(11)：1004-1007,4.DOI:10.3969/j.issn.1671-9638.2017.11.003
血培养分离肠球菌属细菌的分布及耐药性
Distribution and antimicrobial resistance of Enterococcus spp.isolated from blood culture
摘要
Abstract
Objective To understand the clinical distribution and antimicrobial resistance of Enterococcus spp.isolated from blood culture.Methods Enterococcus spp.isolated from blood culture specimens of hospitalized patients between January 2012 and December 2016 was analyzed,antimicrobial susceptibility testing results were analyzed.Results A total of 139 strains of Enterococcus spp.were isolated,including 78 strains of Enterococcus faecium (E.faecium),60 Enterococcus faecalis (E.faecalis),and 1 Enterococcus avium (E.avium),accounting for 56.11％,43.17％,and 0.72％ respectively;56.83％ of patients were ＞60 years and 17.27％ were ≤28 days.The main department sources of strains were intensive care unit and neonatal department,accounting for 34.53％ and 18.70％respectively.There was only 1 strain of E.avium,which was isolated from neonatal department.Resistance rates of E.faecium to penicillin,ampicillin,levofloxacin,ciprofloxacin,moxifloxacin,and nitrofurantoin were all higher than E.faecalis(all P＜0.05),while resistance rate to tetracycline was lower than E.faecalis(P =0.001).Resistance rates of E.faecium to vancomycin and linezolid were 2.56％ and 6.41％ respectively;resistance rates of E.faecalis to vancomycin and linezolid were 0 and 3.33％ respectively.Conclusion E.faecium and E.faecalis are the main Enterococcus spp.isolated from blood culture,most are isolated from the elderly patients and newborns.Resistance rates of E.faecium to most antimicrobial agents are higher than E.faecalis,resistance rates of E.faecium and E.faecalis to linezolid are both higher than resistance rates to vancomycin,key monitoring needs to be continued.关键词
血培养/肠球菌属/屎肠球菌/粪肠球菌/耐药性/抗药性,微生物Key words
blood culture/Enterococcus spp./Enterococcus faecium/Enterococcus faecalis/drug resistance,microbial分类
医药卫生引用本文复制引用
陈胜会,董亮,张秀红,耿先龙..血培养分离肠球菌属细菌的分布及耐药性[J].中国感染控制杂志,2017,16(11):1004-1007,4.基金项目
国家自然科学基金(81400054) （81400054）
无锡市科技发展指导性计划(CSZ0N1604) （CSZ0N1604）
