中国感染控制杂志2017，Vol.16Issue(11)：1065-1068,1077,5.DOI:10.3969/j.issn.1671-9638.2017.11.017
颌面部感染的病原菌及耐药性
Pathogens and antimicrobial resistance in maxillofacial infection
摘要
Abstract
Objective To investigate the distribution and antimicrobial susceptibility of pathogens causing maxillofacial infection in patients,and provide evidence for rational use of antimicrobial agents in clinical practice.Methods Specimens of patients infected with oral and maxillofacial infection in a hospital between January 2012 and December 2016 were performed microbial culture,pathogens were identified and performed antimicrobial susceptibility testing,distribution of pathogens and antimicrobial resistance were analyzed.Results Of 882 patients with maxillofacial infection,male and female accounted for 32.20％ and 67.80％ respectively;35.38％ and 32.65％ of patients aged ～40 years and ～60 years respectively;a total of 145 strains were isolated,88(60.69 ％) of which were gram-negative bacteria,mainly Klebsiella pneumoniae and Pseudomonas aeruginosa;56 (38.62 ％) of which were gram-positive bacteria,mainly Staphylococcus aureus.Resistance rates of Klebsiella pneumoniae to 16 kinds of an timicrobial agents were a11＜50％,resistance rates to imipenem and meropenem were the lowest,both were 3.45％,1 1 strains were extended-spectrum β-lactamases-producing strains;resistance rates of Pseudomonas aeruginosa to 10 kinds of antimicrobial agents were all＜40％.Staphylococcus aureus was susceptible to tigecycline,linezolid,and vancomycin,resistance rate to penicillin was the highest (66.67％),resistance rate to oxacillin was 20.83％.Conclusion The main pathogens causing oral and maxillofacial infection are gram negative bacteria,different pathogens have different antimicrobial resistance,antimicrobial agents should be used rationally during clinical treatment according to antimicrobial susceptibility testing result.关键词
颌面部感染/病原菌/耐药性/抗药性,微生物/合理用药Key words
maxillofacial infection/pathogen/drug resistance, microbial/rational antimicrobial use分类
医药卫生引用本文复制引用
刘春林,张莉,陈弟,徐红云,张唤,李红,方玉飞,邓德耀..颌面部感染的病原菌及耐药性[J].中国感染控制杂志,2017,16(11):1065-1068,1077,5.基金项目
云南省教育厅科学研究基金项目(2013Y285) （2013Y285）
