中国康复理论与实践2018，Vol.24Issue(1)：90-92,3.DOI:10.3969/j.issn.1006-9771.2018.01.017
低氧预处理与高氧预处理在脊髓损伤后神经保护作用的相关研究进展
Research Related to Neural Protection of Hypoxic and Hyperoxic Preconditioning after Spinal Cord Injury (review)
张雯秀 1张妍 1张衍军 2吴启超 2刘亚东 2刘宗建 1关云 1陈学明1
作者信息
- 1. 首都医科大学附属北京潞河医院, 中心实验室,北京市101149
- 2. 首都医科大学附属北京潞河医院, 脊柱外科,北京市101149
- 折叠
摘要
Abstract
Repeated acute intermittent hypoxia promotes the expression of growth factors and neurotrophic factors, as well as the key molecules for neural protection and plasticity. Hypoxic preconditioning may improve the survival rate of transplant-ed stem cells and protect the neural function. Meanwhile, acute intermittent hypoxia can be an approach to improve re-spiratory function after spinal cord injury. Hyperbaric oxygen may improve the neural tolerance to hypoxia and isch-emia, to protect the structure of cells and tissues, and promote the neuranagenesis. It is important to study the role of hy-poxic and hyperoxic preconditioning in spinal cord injury.关键词
脊髓损伤/预处理/低氧/高氧/血管内皮生长因子/缺氧诱导因子-1/干细胞/综述Key words
spinal cord injury/preconditioning/hypoxia/hyperoxia/vascular endothelial growth factor/hypoxia induc-ible factor-1/stem cells/review分类
医药卫生引用本文复制引用
张雯秀,张妍,张衍军,吴启超,刘亚东,刘宗建,关云,陈学明..低氧预处理与高氧预处理在脊髓损伤后神经保护作用的相关研究进展[J].中国康复理论与实践,2018,24(1):90-92,3.
