中国中西医结合影像学杂志2018，Vol.16Issue(1)：4-7,4.DOI:10.3969/j.issn.1672-0512.2018.01.002
兔脑微出血的SWI、MRI常规序列表现及与病理的对照研究
Comparative study of features of MRI different sequences and pathology in rabbits cerebral microbleeds
高玉杰 1王杰 1吕兴隆1
作者信息
- 1. 内蒙古自治区赤峰市医院CT室,内蒙古 赤峰 024000
- 折叠
摘要
Abstract
Objective:Through the establishment of the model of rabbit brain microbleeds (CMBs),the difference of the detec-tion rate of CMBs was compared in different sequences of MRI. And the volume of each sequence and pathological CMBs vol-ume were measured. To explore whether it exists or not of the image amplification effect of magnetic SWI to CMBs. Methods:Forty new Zealand white rabbits aged 12 months were selected,they were divided into control group (5 cases) and experimen-tal group (35 cases) randomly. The control group only had drilling,needle,no injection of blood,and experimental group had drilling,needle,and injection of blood. The MRI scanning was performed at 1 hour (ultra-acute phase),48 hours (acute phase), 15 days (subacute phase) and 35 days (chronic phase) after blood injection. Then,the MRI images and pathological character-istics were observed and volume measurement were performed. Results:SWI sequence showed higher detection rate than con-ventional T1WI and T2WI sequences (100％ and 70.59％,respectively). SWI sequence had magnetic sensitivity amplification effect to the micro bleeding lesion,the average magnification was (1.74±0.77) times. Conclusions:SWI sequence detection rate is more sensitive than conventional sequence to the CMBs,and is a very sensitive sequence for detecting intracranial CMBs. SWI sequence has magnetic sensitivity amplification effect to CMBs and exaggerated the actual volume of CMBs.关键词
磁共振成像/脑出血/模型,动物Key words
Magnetic resonance Imaging/Cerebral hemorrhage/Models/animal引用本文复制引用
高玉杰,王杰,吕兴隆..兔脑微出血的SWI、MRI常规序列表现及与病理的对照研究[J].中国中西医结合影像学杂志,2018,16(1):4-7,4.
