浙江医学2017，Vol.39Issue(23)：2093-2097,5.DOI:10.12056/j.issn.1006-2785.2017.39.23.2017-550
注意缺陷多动障碍的视听注意反应与P300的相关性研究
Correlation of visual event-related potential P300 with audio-visual continuous performance test in children with attention deficit hyperactivity disorder
摘要
Abstract
Objective To investigate the correlation of visual event-related potential P300 with integrated visual auditory continuous performance test (IVA-CPT) in children with attention deficit hyperactivity disorder (ADHD).Methods Thirty children with ADHD and 30 normal children (control group) were enrolled in the study.The visual oddball paradigm was applied,P300 was measured;and the IVA-CPT and SNAP-IV was assessed in all patients and controls.Results The full and secondary scales for attention and response accuracy on the IVA-CPT in children with ADHD were significantly lower compared to normal controls (P＜ 0.01).Children with ADHD showed a significantly longer latency and lower amplitude of P300 compared to normal children,especially for Cz (P＜0.05 or P＜0.01).There were no differences in the area below the wave amplitude between children with ADHD and controls.The visual attention quotient and visual response control quotient were positively correlated with P300(P＜0.05 and P＜0.01),and negatively correlated with the latency of P300 (P＜0.01).Conclusion The endogenous ERPs (P300) is significantly affected in children with ADHD;the increased latency of P300 suggests a slower processing speed,and decreased P300 amplitude suggests the inhibitory control in children with ADHD.These results indicate a neurocognitive abnormality in ADHD.关键词
注意缺陷多动障碍/事件相关电位/P300/注意缺陷多动障碍筛查量表/视听整合持续操作测验/注意功能Key words
Attention deficit hyperactivity disorder/Event-related potentials/P300/SNAP-IV/IVA-CPT/Attention引用本文复制引用
陶丹红,吴绪旭,石敏,邹莹,孔微,韩耀静,陶明..注意缺陷多动障碍的视听注意反应与P300的相关性研究[J].浙江医学,2017,39(23):2093-2097,5.基金项目
浙江省自然科学基金(LY13H090012) （LY13H090012）
